Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review

Metabolic syndrome (MetS), also known as syndrome X, is a significant risk factor for cardiovascular disease incidence and mortality. Increasing age, obesity, physical inactivity, smoking, and positive family history are the risk factors associated with MetS, which increases the risk of diabetes, ca...

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Main Authors: Fatemeh Yarmohammadi, Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-04-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_17743_73b548e00779bc656e273d38c7211c9d.pdf
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spelling doaj-c5a45c6cca134d26a850bb012cd8ab432021-04-04T04:22:13ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences 2008-38662008-38742021-04-0124442042710.22038/ijbms.2021.50276.1145217743Effect of eggplant (Solanum melongena) on the metabolic syndrome: A reviewFatemeh Yarmohammadi0Mahboobeh Ghasemzadeh Rahbardar1Hossein Hosseinzadeh2Student Research Committee, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranMetabolic syndrome (MetS), also known as syndrome X, is a significant risk factor for cardiovascular disease incidence and mortality. Increasing age, obesity, physical inactivity, smoking, and positive family history are the risk factors associated with MetS, which increases the risk of diabetes, cardiovascular disease, hypertension, hyperlipidemia, and obesity. Chemical compounds in the treatment of metabolic complications are associated with a lack of efficacy and severe side effects. Numerous studies have described the importance of herbs and natural products to treat human diseases. Therefore, nowadays, herbs-based diets and herbal medicines are recommended for the management of various diseases. The protective effects of several herbs have been reported against MetS such as rosemary, avocado, and silymarin. Eggplant (Solanum melongena) is a rich source of phenolic and alkaloid compounds. It possesses various pharmacological effects, including, anti-oxidant, antidiabetic, antihypertensive, and antihyperlipidemic, which has been supported by numerous investigations. In this review, we evaluated the effects of eggplant on MetS and its complications comprising diabetes, high blood pressure, hyperlipidemia, and obesity. According to these studies, eggplant can control diabetes through the anti-oxidative properties and inhibition of α-amylase and α-glucosidase activity. Also, eggplant has exerted an antihypertensive effect via ACE inhibitory activity. Eggplant may have shown protective effects on hyperlipidemia and obesity via the induction of lipoprotein lipase activity and the reduction of pancreatic lipase activity.Eggplant can be useful in the treatment of MetS and its complications.https://ijbms.mums.ac.ir/article_17743_73b548e00779bc656e273d38c7211c9d.pdfantihypertensiveantihyperlipidemicauberginediabeteseggplantmetabolic syndromesolanum melongena
collection DOAJ
language English
format Article
sources DOAJ
author Fatemeh Yarmohammadi
Mahboobeh Ghasemzadeh Rahbardar
Hossein Hosseinzadeh
spellingShingle Fatemeh Yarmohammadi
Mahboobeh Ghasemzadeh Rahbardar
Hossein Hosseinzadeh
Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review
Iranian Journal of Basic Medical Sciences
antihypertensive
antihyperlipidemic
aubergine
diabetes
eggplant
metabolic syndrome
solanum melongena
author_facet Fatemeh Yarmohammadi
Mahboobeh Ghasemzadeh Rahbardar
Hossein Hosseinzadeh
author_sort Fatemeh Yarmohammadi
title Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review
title_short Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review
title_full Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review
title_fullStr Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review
title_full_unstemmed Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review
title_sort effect of eggplant (solanum melongena) on the metabolic syndrome: a review
publisher Mashhad University of Medical Sciences
series Iranian Journal of Basic Medical Sciences
issn 2008-3866
2008-3874
publishDate 2021-04-01
description Metabolic syndrome (MetS), also known as syndrome X, is a significant risk factor for cardiovascular disease incidence and mortality. Increasing age, obesity, physical inactivity, smoking, and positive family history are the risk factors associated with MetS, which increases the risk of diabetes, cardiovascular disease, hypertension, hyperlipidemia, and obesity. Chemical compounds in the treatment of metabolic complications are associated with a lack of efficacy and severe side effects. Numerous studies have described the importance of herbs and natural products to treat human diseases. Therefore, nowadays, herbs-based diets and herbal medicines are recommended for the management of various diseases. The protective effects of several herbs have been reported against MetS such as rosemary, avocado, and silymarin. Eggplant (Solanum melongena) is a rich source of phenolic and alkaloid compounds. It possesses various pharmacological effects, including, anti-oxidant, antidiabetic, antihypertensive, and antihyperlipidemic, which has been supported by numerous investigations. In this review, we evaluated the effects of eggplant on MetS and its complications comprising diabetes, high blood pressure, hyperlipidemia, and obesity. According to these studies, eggplant can control diabetes through the anti-oxidative properties and inhibition of α-amylase and α-glucosidase activity. Also, eggplant has exerted an antihypertensive effect via ACE inhibitory activity. Eggplant may have shown protective effects on hyperlipidemia and obesity via the induction of lipoprotein lipase activity and the reduction of pancreatic lipase activity.Eggplant can be useful in the treatment of MetS and its complications.
topic antihypertensive
antihyperlipidemic
aubergine
diabetes
eggplant
metabolic syndrome
solanum melongena
url https://ijbms.mums.ac.ir/article_17743_73b548e00779bc656e273d38c7211c9d.pdf
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