Ribosomal DNA copy number is associated with P53 status and levels of heavy metals in gastrectomy specimens from gastric cancer patients

Ribosomal DNA copy number is associated with P53 status and levels of heavy metals in gastrectomy specimens from gastric cancer patients

The ribosomal DNA (rDNA) can act as a sensor and responder of cancer-associated stress. Here we investigated rDNA copy number in gastric cancers and its association with existing biomarkers and metals exposure. This study was performed on paired tumor and adjacent normal tissues obtained from 65 gas...

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Bibliographic Details
Main Authors: Lingfang Feng, Jing Du, Chunji Yao, Zhaoqiang Jiang, Tao Li, Quan Zhang, Xinnian Guo, Min Yu, Hailing Xia, Li Shi, Junlin Jia, Yan Tong, Li Ju, Jiaqi Liu, Jianlin Lou, Bernardo Lemos
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019339091

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