Hypophosphatasia in children: Diagnostic problems and treatment prospects
The paper gives up-to-date information on hypophosphatasia in children. It represents the results of genetic studies, the pathogene-sis, clinical manifestations, classification, treatment, and prevention of the disease. Particular emphasis is placed on whether clinical trials of novel biological age...
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2016-03-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
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| Online Access: | https://www.ped-perinatology.ru/jour/article/view/81 |
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Article |
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doaj-c5aa310e75834807b1482cea28da170c2021-07-28T16:27:42ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282016-03-01601232674Hypophosphatasia in children: Diagnostic problems and treatment prospectsP. V. Novikov0Research Clinical Institute of Pediatrics, MoscowThe paper gives up-to-date information on hypophosphatasia in children. It represents the results of genetic studies, the pathogene-sis, clinical manifestations, classification, treatment, and prevention of the disease. Particular emphasis is placed on whether clinical trials of novel biological agents for the pathogenetic therapy of hypophosphatasia (enzyme replacement therapy) may be conducted.https://www.ped-perinatology.ru/jour/article/view/81childrenhypophosphatasiamonogenic diseasesalkalinephosphatasepathogenetic therapyenzyme replacement therapyasfotase alfa. |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
P. V. Novikov |
| spellingShingle |
P. V. Novikov Hypophosphatasia in children: Diagnostic problems and treatment prospects Rossijskij Vestnik Perinatologii i Pediatrii children hypophosphatasia monogenic diseases alkalinephosphatase pathogenetic therapy enzyme replacement therapy asfotase alfa. |
| author_facet |
P. V. Novikov |
| author_sort |
P. V. Novikov |
| title |
Hypophosphatasia in children: Diagnostic problems and treatment prospects |
| title_short |
Hypophosphatasia in children: Diagnostic problems and treatment prospects |
| title_full |
Hypophosphatasia in children: Diagnostic problems and treatment prospects |
| title_fullStr |
Hypophosphatasia in children: Diagnostic problems and treatment prospects |
| title_full_unstemmed |
Hypophosphatasia in children: Diagnostic problems and treatment prospects |
| title_sort |
hypophosphatasia in children: diagnostic problems and treatment prospects |
| publisher |
Ltd. “The National Academy of Pediatric Science and Innovation” |
| series |
Rossijskij Vestnik Perinatologii i Pediatrii |
| issn |
1027-4065 2500-2228 |
| publishDate |
2016-03-01 |
| description |
The paper gives up-to-date information on hypophosphatasia in children. It represents the results of genetic studies, the pathogene-sis, clinical manifestations, classification, treatment, and prevention of the disease. Particular emphasis is placed on whether clinical trials of novel biological agents for the pathogenetic therapy of hypophosphatasia (enzyme replacement therapy) may be conducted. |
| topic |
children hypophosphatasia monogenic diseases alkalinephosphatase pathogenetic therapy enzyme replacement therapy asfotase alfa. |
| url |
https://www.ped-perinatology.ru/jour/article/view/81 |
| work_keys_str_mv |
AT pvnovikov hypophosphatasiainchildrendiagnosticproblemsandtreatmentprospects |
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