Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling

HU is among the most conserved and abundant nucleoid-associated proteins in eubacteria. Here the authors investigate the role of histone-like proteins (HU) in the 3D organization of the bacteria DNA and show via soft X-ray tomography the process of nucleoid remodeling.

Bibliographic Details
Main Authors:	Soumya G. Remesh, Subhash C. Verma, Jian-Hua Chen, Axel A. Ekman, Carolyn A. Larabell, Sankar Adhya, Michal Hammel
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-16724-5

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spelling	doaj-c5ba312025fb45d398cd579a218e48082021-06-13T11:18:55ZengNature Publishing GroupNature Communications2041-17232020-06-0111111210.1038/s41467-020-16724-5Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundlingSoumya G. Remesh0Subhash C. Verma1Jian-Hua Chen2Axel A. Ekman3Carolyn A. Larabell4Sankar Adhya5Michal Hammel6Laboratory of Molecular Biology, Center for Cancer Research, National Cancer InstituteLaboratory of Molecular Biology, Center for Cancer Research, National Cancer InstituteMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National LaboratoryMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National LaboratoryMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National LaboratoryLaboratory of Molecular Biology, Center for Cancer Research, National Cancer InstituteMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National LaboratoryHU is among the most conserved and abundant nucleoid-associated proteins in eubacteria. Here the authors investigate the role of histone-like proteins (HU) in the 3D organization of the bacteria DNA and show via soft X-ray tomography the process of nucleoid remodeling.https://doi.org/10.1038/s41467-020-16724-5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Soumya G. Remesh Subhash C. Verma Jian-Hua Chen Axel A. Ekman Carolyn A. Larabell Sankar Adhya Michal Hammel
spellingShingle	Soumya G. Remesh Subhash C. Verma Jian-Hua Chen Axel A. Ekman Carolyn A. Larabell Sankar Adhya Michal Hammel Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling Nature Communications
author_facet	Soumya G. Remesh Subhash C. Verma Jian-Hua Chen Axel A. Ekman Carolyn A. Larabell Sankar Adhya Michal Hammel
author_sort	Soumya G. Remesh
title	Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling
title_short	Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling
title_full	Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling
title_fullStr	Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling
title_full_unstemmed	Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling
title_sort	nucleoid remodeling during environmental adaptation is regulated by hu-dependent dna bundling
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-06-01
description	HU is among the most conserved and abundant nucleoid-associated proteins in eubacteria. Here the authors investigate the role of histone-like proteins (HU) in the 3D organization of the bacteria DNA and show via soft X-ray tomography the process of nucleoid remodeling.
url	https://doi.org/10.1038/s41467-020-16724-5
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Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling

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