Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation

Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation

Background/Aims: This study investigated the effect of consecutive superovulation on the ovaries and established a premature ovarian failure (POF) model in mice. Methods: The mouse POF model was induced by 5-15 consecutive superovulation treatments with pregnant mare serum gonadotropin (PMSG), human...

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Bibliographic Details
Main Authors: Xiaowei Nie, Youjin Dai, Yuan Zheng, Dan Bao, Qin Chen, Yuan Yin, Heling Fu, Daorong Hou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ovulation
Oxidative stress
Apoptosis
Premature ovarian failure
Ovary aging
Online Access:https://www.karger.com/Article/FullText/495895

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