Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment

Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment

Abstract Background Opioids are the most effective drugs commonly prescribed to treat pain. Due to their addictive nature, opioid pain relievers are now second to marijuana, ahead of cocaine with respect to dependence. Ours and other studies suggest potential toxic effects of chronic opioid administ...

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Bibliographic Details
Main Authors:	Ruping Fan, Lisa M. Schrott, Stephen Snelling, John Felty, Derrel Graham, Patrick L. McGauly, Thomas Arnold, Nadejda L. Korneeva
Format:	Article
Language:	English
Published:	BMC 2020-01-01
Series:	BMC Neuroscience
Subjects:	Oxycodone Opioid Cortex Oxidative stress Integrated stress response Carbonyl-protein
Online Access:	https://doi.org/10.1186/s12868-020-0552-2

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