The Role of the Plasminogen Activation System in Angioedema: Novel Insights on the Pathogenesis

<b>: </b>The main physiological functions of plasmin, the active form of its proenzyme plasminogen, are blood clot fibrinolysis and restoration of normal blood flow. The plasminogen activation (PA) system includes urokinase-type plasminogen activator (uPA), tissue-type PA (tPA), and two...

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Bibliographic Details
Main Authors: Filomena Napolitano, Nunzia Montuori
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
tPA
Online Access:https://www.mdpi.com/2077-0383/10/3/518