Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats

The present work reports the effect of aubergine extract on serum and hepatic cholesterol and triglycerides levels in adult rats. Fisher rats were divided into three groups: the first one received a normolipidic diet and water , serving as a control; the other two received a hypercholesterolaemic di...

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Main Authors: Marcelo E Silva, Rinaldo C Santos, Maureen C O'Leary, Ronald S Santos
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 1999-01-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131999000300011
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spelling doaj-c5e338d302124c819cc9920a6517eb172020-11-24T23:38:44ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1516-89131678-43241999-01-0142333934210.1590/S1516-89131999000300011Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in ratsMarcelo E SilvaRinaldo C SantosMaureen C O'LearyRonald S SantosThe present work reports the effect of aubergine extract on serum and hepatic cholesterol and triglycerides levels in adult rats. Fisher rats were divided into three groups: the first one received a normolipidic diet and water , serving as a control; the other two received a hypercholesterolaemic diet with 30% vegetable oil and 1% cholesterol, one of these being given water while the other was given an aubergine extract. After 28 days the animals were sacrificed and serum and hepatic cholesterol and triglycerides levels were assessed. The obtained results indicated that under the experimental conditions employed, the aubergine extract increased serum and decreased hepatic cholesterol and had little or no effect on both serum and hepatic triglycerides.<br>A beringela (Solanum melongena) tem sido apontada como possuidora da capacidade de reduzir o colesterol sérico. O chá do vegetal vem sendo utilizado com este propósito, devido ao interesse na descoberta de formas alternativas para o controle da hipercolesterolemia. No presente trabalho testou-se o efeito do chá de beringela nos níveis séricos e hepáticos de colesterol e triglicerídeos em ratos adultos. Ratos Fisher foram divididos em três grupos: o primeiro recebeu dieta normolipídica ad libitum e água para beber, funcionando como controle; os outros dois receberam dieta hipercolesterolêmica com 30% de óleo vegetal e 1% de colesterol, sendo dada a um destes grupos água para beber, enquanto que o outro recebeu apenas chá de beringela. Após 28 dias os animais foram sacrificados e dosaram-se os níveis de colesterol e triglicerídeos séricos e hepáticos. Os resultados obtidos indicam que, nas condições experimentais utilizadas, o chá de beringela eleva o colesterol sérico, reduz o hepático e tem pouco ou nenhum efeito sobre os triglicerídeos, tanto séricos quanto hepáticos.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131999000300011aubergineeggplantSolanum melongenaserum cholesterolhepatic cholesterol
collection DOAJ
language English
format Article
sources DOAJ
author Marcelo E Silva
Rinaldo C Santos
Maureen C O'Leary
Ronald S Santos
spellingShingle Marcelo E Silva
Rinaldo C Santos
Maureen C O'Leary
Ronald S Santos
Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
Brazilian Archives of Biology and Technology
aubergine
eggplant
Solanum melongena
serum cholesterol
hepatic cholesterol
author_facet Marcelo E Silva
Rinaldo C Santos
Maureen C O'Leary
Ronald S Santos
author_sort Marcelo E Silva
title Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
title_short Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
title_full Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
title_fullStr Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
title_full_unstemmed Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
title_sort effect of aubergine (solanum melongena) on serum and hepatic cholesterol and triglycerides in rats
publisher Instituto de Tecnologia do Paraná (Tecpar)
series Brazilian Archives of Biology and Technology
issn 1516-8913
1678-4324
publishDate 1999-01-01
description The present work reports the effect of aubergine extract on serum and hepatic cholesterol and triglycerides levels in adult rats. Fisher rats were divided into three groups: the first one received a normolipidic diet and water , serving as a control; the other two received a hypercholesterolaemic diet with 30% vegetable oil and 1% cholesterol, one of these being given water while the other was given an aubergine extract. After 28 days the animals were sacrificed and serum and hepatic cholesterol and triglycerides levels were assessed. The obtained results indicated that under the experimental conditions employed, the aubergine extract increased serum and decreased hepatic cholesterol and had little or no effect on both serum and hepatic triglycerides.<br>A beringela (Solanum melongena) tem sido apontada como possuidora da capacidade de reduzir o colesterol sérico. O chá do vegetal vem sendo utilizado com este propósito, devido ao interesse na descoberta de formas alternativas para o controle da hipercolesterolemia. No presente trabalho testou-se o efeito do chá de beringela nos níveis séricos e hepáticos de colesterol e triglicerídeos em ratos adultos. Ratos Fisher foram divididos em três grupos: o primeiro recebeu dieta normolipídica ad libitum e água para beber, funcionando como controle; os outros dois receberam dieta hipercolesterolêmica com 30% de óleo vegetal e 1% de colesterol, sendo dada a um destes grupos água para beber, enquanto que o outro recebeu apenas chá de beringela. Após 28 dias os animais foram sacrificados e dosaram-se os níveis de colesterol e triglicerídeos séricos e hepáticos. Os resultados obtidos indicam que, nas condições experimentais utilizadas, o chá de beringela eleva o colesterol sérico, reduz o hepático e tem pouco ou nenhum efeito sobre os triglicerídeos, tanto séricos quanto hepáticos.
topic aubergine
eggplant
Solanum melongena
serum cholesterol
hepatic cholesterol
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131999000300011
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AT maureencoleary effectofauberginesolanummelongenaonserumandhepaticcholesterolandtriglyceridesinrats
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