Positively charged residues are the major determinants of ribosomal velocity.

Both for understanding mechanisms of disease and for the design of transgenes, it is important to understand the determinants of ribosome velocity, as changes in the rate of translation are important for protein folding, error attenuation, and localization. While there is great variation in ribosoma...

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Bibliographic Details
Main Authors: Catherine A Charneski, Laurence D Hurst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3595205?pdf=render