Signalling Pathways that Inhibit the Capacity of Precursor Cells for Myelin Repair

Signalling Pathways that Inhibit the Capacity of Precursor Cells for Myelin Repair

In demyelinating disorders such as Multiple Sclerosis (MS), targets of injury are myelin and oligodendrocytes, leading to severe neurological dysfunction. Regenerative therapies aimed at promoting oligodendrocyte maturation and remyelination are promising strategies for treatment in demyelinating di...

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Bibliographic Details
Main Authors:	Jennifer K. Sabo, Holly S. Cate
Format:	Article
Language:	English
Published:	MDPI AG 2013-01-01
Series:	International Journal of Molecular Sciences
Subjects:	oligodendrocyte progenitor cell (OPC) neural precursor cell (NPC) bone morphogenic protein (BMP) central nervous system (CNS)
Online Access:	http://www.mdpi.com/1422-0067/14/1/1031

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