Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review
Background Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise t...
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Format: | Article |
Language: | English |
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BMJ Publishing Group
2020-11-01
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Series: | BMJ Global Health |
Online Access: | https://gh.bmj.com/content/5/11/e003716.full |
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language |
English |
format |
Article |
sources |
DOAJ |
author |
Sanjeev Krishna Andrew Shennan Helena Boene Marianne Vidler Laura A Magee Esperanca Sevene Peter von Dadelszen Eusébio Macete Anifa Vala Salésio Macuacua Sónia Maculuve Jeffrey Bone Beth A Payne Jane Sandall Veronique Filippi Lucilla Poston Kate Bramham Lucy Chappell Melisa Martinez-Alvarez Geoffrey Omuse Guy Whitley Hannah Blencowe Sean Beevers Rachel Craik Marleen Temmerman Jeffrey N Bone Kelly Pickerill Mai-Lei Woo Kinshella William Stones Angela Koech Etyang Anna Roca Donna Russell Rachel M Tribe Umberto D’Alessandro Hawanatu Jah Ofordile Oguchukwu Andrew Prentice Brahima Diallo Adbul Sesey Kodou Lette Alpha Bah Chilel Sanyang Angela Koech Etyang Peris Musitia Mary Amondi David Chege Patricia Okiro Sikolia Wanyonyi Paulo Chin Corssino Tchavana Lazaro Quimice Inacio Mandomando Carla Carillho Peter von Dadelszen Meriel Flint-O’Kane Amber Strang Marina Daniele Tatenda Makanga Liberty Makacha Yolisa Dube Newton Nyapwere Rachel Tribe Sophie Moore Tatiana Salisbury Ben Barratt Aris Papageorgiou Alison Noble Joy Lawn Matt Silver Matthew Chico Judith Cartwright Jing (Larry) Li Mai-Lei (Maggie) Woo Kinshella Domena Tu Warancha Tumtaweetikul Marie-Laure Volvert |
spellingShingle |
Sanjeev Krishna Andrew Shennan Helena Boene Marianne Vidler Laura A Magee Esperanca Sevene Peter von Dadelszen Eusébio Macete Anifa Vala Salésio Macuacua Sónia Maculuve Jeffrey Bone Beth A Payne Jane Sandall Veronique Filippi Lucilla Poston Kate Bramham Lucy Chappell Melisa Martinez-Alvarez Geoffrey Omuse Guy Whitley Hannah Blencowe Sean Beevers Rachel Craik Marleen Temmerman Jeffrey N Bone Kelly Pickerill Mai-Lei Woo Kinshella William Stones Angela Koech Etyang Anna Roca Donna Russell Rachel M Tribe Umberto D’Alessandro Hawanatu Jah Ofordile Oguchukwu Andrew Prentice Brahima Diallo Adbul Sesey Kodou Lette Alpha Bah Chilel Sanyang Angela Koech Etyang Peris Musitia Mary Amondi David Chege Patricia Okiro Sikolia Wanyonyi Paulo Chin Corssino Tchavana Lazaro Quimice Inacio Mandomando Carla Carillho Peter von Dadelszen Meriel Flint-O’Kane Amber Strang Marina Daniele Tatenda Makanga Liberty Makacha Yolisa Dube Newton Nyapwere Rachel Tribe Sophie Moore Tatiana Salisbury Ben Barratt Aris Papageorgiou Alison Noble Joy Lawn Matt Silver Matthew Chico Judith Cartwright Jing (Larry) Li Mai-Lei (Maggie) Woo Kinshella Domena Tu Warancha Tumtaweetikul Marie-Laure Volvert Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review BMJ Global Health |
author_facet |
Sanjeev Krishna Andrew Shennan Helena Boene Marianne Vidler Laura A Magee Esperanca Sevene Peter von Dadelszen Eusébio Macete Anifa Vala Salésio Macuacua Sónia Maculuve Jeffrey Bone Beth A Payne Jane Sandall Veronique Filippi Lucilla Poston Kate Bramham Lucy Chappell Melisa Martinez-Alvarez Geoffrey Omuse Guy Whitley Hannah Blencowe Sean Beevers Rachel Craik Marleen Temmerman Jeffrey N Bone Kelly Pickerill Mai-Lei Woo Kinshella William Stones Angela Koech Etyang Anna Roca Donna Russell Rachel M Tribe Umberto D’Alessandro Hawanatu Jah Ofordile Oguchukwu Andrew Prentice Brahima Diallo Adbul Sesey Kodou Lette Alpha Bah Chilel Sanyang Angela Koech Etyang Peris Musitia Mary Amondi David Chege Patricia Okiro Sikolia Wanyonyi Paulo Chin Corssino Tchavana Lazaro Quimice Inacio Mandomando Carla Carillho Peter von Dadelszen Meriel Flint-O’Kane Amber Strang Marina Daniele Tatenda Makanga Liberty Makacha Yolisa Dube Newton Nyapwere Rachel Tribe Sophie Moore Tatiana Salisbury Ben Barratt Aris Papageorgiou Alison Noble Joy Lawn Matt Silver Matthew Chico Judith Cartwright Jing (Larry) Li Mai-Lei (Maggie) Woo Kinshella Domena Tu Warancha Tumtaweetikul Marie-Laure Volvert |
author_sort |
Sanjeev Krishna |
title |
Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review |
title_short |
Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review |
title_full |
Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review |
title_fullStr |
Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review |
title_full_unstemmed |
Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic review |
title_sort |
pregnancy cohorts and biobanking in sub-saharan africa: a systematic review |
publisher |
BMJ Publishing Group |
series |
BMJ Global Health |
issn |
2059-7908 |
publishDate |
2020-11-01 |
description |
Background Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise to low-resource settings. We conducted a systematic review to identify prospective pregnancy cohorts in sub-Saharan Africa (SSA) that include biobanked samples with potential to enhance discovery science opportunity.Methods Inclusion criteria were prospective data collection during pregnancy, with associated biobanking in SSA. Data sources included: scientific databases (with comprehensive search terms), grey literature, hand searching applicable reference lists and expert input. Results were screened in a three-stage process based on title, abstract and full text by two independent reviewers. The review is registered on PROSPERO (CRD42019147483).Results Fourteen SSA studies met the inclusion criteria from database searches (n=8), reference list searches (n=2) and expert input (n=4). Three studies have ongoing data collection. The most represented countries were South Africa and Mozambique (Southern Africa) (n=3), Benin (Western Africa) (n=4) and Tanzania (Eastern Africa) (n=4); including an estimated 31 763 women. Samples commonly collected were blood, cord blood and placenta. Seven studies collected neonatal samples. Common clinical outcomes included maternal and perinatal mortality, malaria and preterm birth.Conclusions Increasingly numerous pregnancy cohorts in SSA that include biobanking are generating a uniquely valuable resource for collaborative discovery science, and improved understanding of the high regional risks of maternal, fetal and neonatal morbidity and mortality. Future studies should align protocols and consider their added value and distinct contributions. |
url |
https://gh.bmj.com/content/5/11/e003716.full |
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doaj-c62b63165c6b4c26a0ac112213dffda02021-01-21T21:30:21ZengBMJ Publishing GroupBMJ Global Health2059-79082020-11-0151110.1136/bmjgh-2020-003716Pregnancy cohorts and biobanking in sub-Saharan Africa: a systematic reviewSanjeev KrishnaAndrew ShennanHelena BoeneMarianne Vidler0Laura A Magee1Esperanca Sevene2Peter von Dadelszen3Eusébio MaceteAnifa ValaSalésio MacuacuaSónia MaculuveJeffrey Bone4Beth A PayneJane SandallVeronique FilippiLucilla Poston5Kate BramhamLucy ChappellMelisa Martinez-AlvarezGeoffrey OmuseGuy WhitleyHannah BlencoweSean BeeversRachel Craik6Marleen Temmerman7Jeffrey N Bone8Kelly Pickerill9Mai-Lei Woo Kinshella10William Stones11Angela Koech Etyang12Anna Roca13Donna Russell14Rachel M Tribe15Umberto D’AlessandroHawanatu JahOfordile OguchukwuAndrew PrenticeBrahima DialloAdbul SeseyKodou LetteAlpha BahChilel SanyangAngela Koech EtyangPeris MusitiaMary AmondiDavid ChegePatricia OkiroSikolia WanyonyiPaulo ChinCorssino TchavanaLazaro QuimiceInacio MandomandoCarla CarillhoPeter von DadelszenMeriel Flint-O’KaneAmber StrangMarina DanieleTatenda MakangaLiberty MakachaYolisa DubeNewton NyapwereRachel TribeSophie MooreTatiana SalisburyBen BarrattAris PapageorgiouAlison NobleJoy LawnMatt SilverMatthew ChicoJudith CartwrightJing (Larry) LiMai-Lei (Maggie) Woo KinshellaDomena TuWarancha TumtaweetikulMarie-Laure VolvertDepartment of Obstetrics and Gynaecology, The University of British Columbia, Faculty of Medicine, Vancouver, British Columbia, CanadaDepartment of Women and Children’s Health, King's College London, School of Life Course Sciences, Faculty of Life Sciences and Medicine, London, UKCentro de Investigação em Saúde de Manhiça, Manhiça, Maputo, MozambiqueDepartment of Women and Children’s Health, King's College London, School of Life Course Sciences, Faculty of Life Sciences and Medicine, London, UKObstetrics and Gynecology, The University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Women and Children’s Health, King's College London, School of Life Course Sciences, Faculty of Life Sciences and Medicine, London, UKDepartment of Women and Children’s Health, King's College London, School of Life Course Sciences, Faculty of Life Sciences and Medicine, London, UKDepartment of Obstetrics and Gynaecology, Centre of Excellence in Women and Child Health, Aga Khan University, Nairobi, KenyaDepartment of Obstetrics and Gynaecology, The University of British Columbia, Faculty of Medicine, Vancouver, British Columbia, CanadaDepartment of Obstetrics and Gynaecology, The University of British Columbia, Faculty of Medicine, Vancouver, British Columbia, CanadaDepartment of Obstetrics and Gynaecology, The University of British Columbia, Faculty of Medicine, Vancouver, British Columbia, CanadaCentre for Reproductive Health, University of Malawi College of Medicine, Blantyre, MalawiDepartment of Obstetrics and Gynaecology, Centre of Excellence in Women and Child Health, Aga Khan University, Nairobi, KenyaMedical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The GambiaDonna Russell Consulting, Seattle, Washington, USADepartment of Women and Children’s Health, King's College London, School of Life Course Sciences, Faculty of Life Sciences and Medicine, London, UKBackground Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise to low-resource settings. We conducted a systematic review to identify prospective pregnancy cohorts in sub-Saharan Africa (SSA) that include biobanked samples with potential to enhance discovery science opportunity.Methods Inclusion criteria were prospective data collection during pregnancy, with associated biobanking in SSA. Data sources included: scientific databases (with comprehensive search terms), grey literature, hand searching applicable reference lists and expert input. Results were screened in a three-stage process based on title, abstract and full text by two independent reviewers. The review is registered on PROSPERO (CRD42019147483).Results Fourteen SSA studies met the inclusion criteria from database searches (n=8), reference list searches (n=2) and expert input (n=4). Three studies have ongoing data collection. The most represented countries were South Africa and Mozambique (Southern Africa) (n=3), Benin (Western Africa) (n=4) and Tanzania (Eastern Africa) (n=4); including an estimated 31 763 women. Samples commonly collected were blood, cord blood and placenta. Seven studies collected neonatal samples. Common clinical outcomes included maternal and perinatal mortality, malaria and preterm birth.Conclusions Increasingly numerous pregnancy cohorts in SSA that include biobanking are generating a uniquely valuable resource for collaborative discovery science, and improved understanding of the high regional risks of maternal, fetal and neonatal morbidity and mortality. Future studies should align protocols and consider their added value and distinct contributions.https://gh.bmj.com/content/5/11/e003716.full |