HLA-B*58:01 for allopurinol-induced cutaneous adverse drug reactions: Implication for clinical interpretation in Thailand

HLA-B*58:01 for allopurinol-induced cutaneous adverse drug reactions: Implication for clinical interpretation in Thailand

AbstractBackground: The aim of this study was to investigate the predisposition to different types of allopurinol-induced cutaneous adverse drug reactions (CADR), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) (SJS-TEN, n=13), drug reaction with eosinophilia and systemic...

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Main Authors: Chonlaphat Sukasem, ํYaowaluck Hongkaew, Thawinee Jantararoungtong, Parnrat Kuntawong, Apichaya Puangpetch, Napatrupron Koomdee, Patompong Satapornpong, Patcharin Supapsophon, Jettanong Klaewsongkram, Ticha Rerkpattanapipat
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Pharmacology
Subjects:
Allopurinol
Drug Hypersensitivity
SCAR
dress
Thai
MPE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00186/full

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