Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs
This study investigates the contractile activity of smooth muscle segments of guinea pig pulmonary artery by the method of mechanografy and morphological picture of lungs, airways and blood vessels of the pulmonary circulation under the influence of nanosized magnetite. It is shown that chronic inha...
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Siberian State Medical University (Tomsk)
2012-02-01
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doaj-c669fbd190ba4582acaa6824fae3ebe62021-07-29T08:37:56ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842012-02-01111525810.20538/1682-0363-2012-1-52-58385Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigsA. V. Nosarev0Ye. Ye. Abramenko1L. V. Kapilevich2V. N. Vasiliyev3Ye. Yu. Diyakova4A. M. Tabayeva5T. A. Kironenko6V. V. Perfiliyeva7I.Influence of nanosized magnetite on th V. Milto8Сибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскThis study investigates the contractile activity of smooth muscle segments of guinea pig pulmonary artery by the method of mechanografy and morphological picture of lungs, airways and blood vessels of the pulmonary circulation under the influence of nanosized magnetite. It is shown that chronic inhalation intake of magnetite nanoparticles has a cytotoxic effect, leading to inflammatory changes in the airways, lung parenchyma and pulmonary vessels, as well as a change in contractile activity of the pulmonary artery by the action of neurotransmitters and mediators of exercising their functions under physiological conditions or produced during the inflammatory the process.https://bulletin.tomsk.ru/jour/article/view/407smooth muscle cellspulmonary arterynanoparticlessignalinginflammation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
A. V. Nosarev Ye. Ye. Abramenko L. V. Kapilevich V. N. Vasiliyev Ye. Yu. Diyakova A. M. Tabayeva T. A. Kironenko V. V. Perfiliyeva I.Influence of nanosized magnetite on th V. Milto |
spellingShingle |
A. V. Nosarev Ye. Ye. Abramenko L. V. Kapilevich V. N. Vasiliyev Ye. Yu. Diyakova A. M. Tabayeva T. A. Kironenko V. V. Perfiliyeva I.Influence of nanosized magnetite on th V. Milto Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs Bûlleten' Sibirskoj Mediciny smooth muscle cells pulmonary artery nanoparticles signaling inflammation |
author_facet |
A. V. Nosarev Ye. Ye. Abramenko L. V. Kapilevich V. N. Vasiliyev Ye. Yu. Diyakova A. M. Tabayeva T. A. Kironenko V. V. Perfiliyeva I.Influence of nanosized magnetite on th V. Milto |
author_sort |
A. V. Nosarev |
title |
Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs |
title_short |
Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs |
title_full |
Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs |
title_fullStr |
Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs |
title_full_unstemmed |
Influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs |
title_sort |
influence of nanosized magnetite on the contractile activity of smooth muscle segments of the pulmonary artery of guinea pigs |
publisher |
Siberian State Medical University (Tomsk) |
series |
Bûlleten' Sibirskoj Mediciny |
issn |
1682-0363 1819-3684 |
publishDate |
2012-02-01 |
description |
This study investigates the contractile activity of smooth muscle segments of guinea pig pulmonary artery by the method of mechanografy and morphological picture of lungs, airways and blood vessels of the pulmonary circulation under the influence of nanosized magnetite. It is shown that chronic inhalation intake of magnetite nanoparticles has a cytotoxic effect, leading to inflammatory changes in the airways, lung parenchyma and pulmonary vessels, as well as a change in contractile activity of the pulmonary artery by the action of neurotransmitters and mediators of exercising their functions under physiological conditions or produced during the inflammatory the process. |
topic |
smooth muscle cells pulmonary artery nanoparticles signaling inflammation |
url |
https://bulletin.tomsk.ru/jour/article/view/407 |
work_keys_str_mv |
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