GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration

GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration

Summary: Oligodendrocyte precursor cells (OPCs) are essential for developmental myelination and oligodendrocyte regeneration after CNS injury. These progenitors express calcium-permeable AMPA receptors (AMPARs) and form direct synapses with neurons throughout the CNS, but the roles of this signaling...

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Bibliographic Details
Main Authors: Rabia R. Khawaja, Amit Agarwal, Masahiro Fukaya, Hey-Kyeong Jeong, Scott Gross, Estibaliz Gonzalez-Fernandez, Jonathan Soboloff, Dwight E. Bergles, Shin H. Kang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
oligodendrocyte
OPC
GluA2
remyelination
AMPA receptor
injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004861

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