Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral
The speed and pen-pressure while sketching a spiral are lower among Parkinson’s disease (PD) patients with higher severity of the disease. However, the correlation between these features and the severity level (SL) of PD has been reported to be 0.4. There is a need for identifying parameters with a...
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doaj-c6a8a3bb9e824435bea982b1b29193802020-11-24T23:38:56ZengFrontiers Media S.A.Frontiers in Neurology1664-22952017-09-01810.3389/fneur.2017.00435268142Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a SpiralPoonam Zham0Dinesh K. Kumar1Peter Dabnichki2Sridhar Poosapadi Arjunan3Sanjay Raghav4Sanjay Raghav5School of Engineering, RMIT University, Melbourne, VIC, AustraliaSchool of Engineering, RMIT University, Melbourne, VIC, AustraliaSchool of Engineering, RMIT University, Melbourne, VIC, AustraliaSchool of Engineering, RMIT University, Melbourne, VIC, AustraliaSchool of Engineering, RMIT University, Melbourne, VIC, AustraliaDandenong Neurology, Melbourne, VIC, AustraliaThe speed and pen-pressure while sketching a spiral are lower among Parkinson’s disease (PD) patients with higher severity of the disease. However, the correlation between these features and the severity level (SL) of PD has been reported to be 0.4. There is a need for identifying parameters with a stronger correlation for considering this for accurate diagnosis of the disease. This study has proposed the use of the Composite Index of Speed and Pen-pressure (CISP) of sketching as a feature for analyzing the severity of PD. A total of 28 control group (CG) and 27 PD patients (total 55 participants) were recruited and assessed for Unified Parkinson’s Disease Rating Scale (UPDRS). They drew guided Archimedean spiral on an A3 sheet. Speed, pen-pressure, and CISP were computed and analyzed to obtain their correlation with severity of the disease. The correlation of speed, pen-pressure, and CISP with the severity of PD was −0.415, −0.584, and −0.641, respectively. Mann–Whitney U test confirmed that CISP was suitable to distinguish between PD and CG, while non-parametric k-sample Kruskal–Wallis test confirmed that it was significantly different for PD SL-1 and PD SL-3. This shows that CISP during spiral sketching may be used to differentiate between CG and PD and between PD SL-1 and PD SL-3 but not SL-2.http://journal.frontiersin.org/article/10.3389/fneur.2017.00435/fullParkinson’skinematic featurespeedpen-pressuredynamic handwriting features |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Poonam Zham Dinesh K. Kumar Peter Dabnichki Sridhar Poosapadi Arjunan Sanjay Raghav Sanjay Raghav |
spellingShingle |
Poonam Zham Dinesh K. Kumar Peter Dabnichki Sridhar Poosapadi Arjunan Sanjay Raghav Sanjay Raghav Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral Frontiers in Neurology Parkinson’s kinematic feature speed pen-pressure dynamic handwriting features |
author_facet |
Poonam Zham Dinesh K. Kumar Peter Dabnichki Sridhar Poosapadi Arjunan Sanjay Raghav Sanjay Raghav |
author_sort |
Poonam Zham |
title |
Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral |
title_short |
Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral |
title_full |
Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral |
title_fullStr |
Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral |
title_full_unstemmed |
Distinguishing Different Stages of Parkinson’s Disease Using Composite Index of Speed and Pen-Pressure of Sketching a Spiral |
title_sort |
distinguishing different stages of parkinson’s disease using composite index of speed and pen-pressure of sketching a spiral |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neurology |
issn |
1664-2295 |
publishDate |
2017-09-01 |
description |
The speed and pen-pressure while sketching a spiral are lower among Parkinson’s disease (PD) patients with higher severity of the disease. However, the correlation between these features and the severity level (SL) of PD has been reported to be 0.4. There is a need for identifying parameters with a stronger correlation for considering this for accurate diagnosis of the disease. This study has proposed the use of the Composite Index of Speed and Pen-pressure (CISP) of sketching as a feature for analyzing the severity of PD. A total of 28 control group (CG) and 27 PD patients (total 55 participants) were recruited and assessed for Unified Parkinson’s Disease Rating Scale (UPDRS). They drew guided Archimedean spiral on an A3 sheet. Speed, pen-pressure, and CISP were computed and analyzed to obtain their correlation with severity of the disease. The correlation of speed, pen-pressure, and CISP with the severity of PD was −0.415, −0.584, and −0.641, respectively. Mann–Whitney U test confirmed that CISP was suitable to distinguish between PD and CG, while non-parametric k-sample Kruskal–Wallis test confirmed that it was significantly different for PD SL-1 and PD SL-3. This shows that CISP during spiral sketching may be used to differentiate between CG and PD and between PD SL-1 and PD SL-3 but not SL-2. |
topic |
Parkinson’s kinematic feature speed pen-pressure dynamic handwriting features |
url |
http://journal.frontiersin.org/article/10.3389/fneur.2017.00435/full |
work_keys_str_mv |
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