The suitability of P. falciparum merozoite surface proteins 1 and 2 as genetic markers for in vivo drug trials in Yemen.

BACKGROUND: The accuracy of the conclusions from in vivo efficacy anti-malarial drug trials depends on distinguishing between recrudescences and re-infections which is accomplished by genotyping genes coding P. falciparum merozoite surface 1 (MSP1) and MSP2. However, the reliability of the PCR analy...

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Bibliographic Details
Main Authors: Nazeh M Al-abd, Mohammed A K Mahdy, Abdulsalam M Q Al-Mekhlafi, Georges Snounou, Nazia B Abdul-Majid, Hesham M Al-Mekhlafi, Mun Y Fong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701615?pdf=render