The suitability of P. falciparum merozoite surface proteins 1 and 2 as genetic markers for in vivo drug trials in Yemen.
BACKGROUND: The accuracy of the conclusions from in vivo efficacy anti-malarial drug trials depends on distinguishing between recrudescences and re-infections which is accomplished by genotyping genes coding P. falciparum merozoite surface 1 (MSP1) and MSP2. However, the reliability of the PCR analy...
Main Authors: | Nazeh M Al-abd, Mohammed A K Mahdy, Abdulsalam M Q Al-Mekhlafi, Georges Snounou, Nazia B Abdul-Majid, Hesham M Al-Mekhlafi, Mun Y Fong |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3701615?pdf=render |
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