Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase

Background and purpose: Carbohydrate hydrolysis enzymes including α-glucosidase and α-amylase are related to type 2 diabetes mellitus. The inhibiting of these enzymes might use for type 2 diabetes mellitus treatment. Experimental approach: N-substituted-acetylpyrrolidine linked with -benzyl- (N-(ben...

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Bibliographic Details
Main Authors: Sompong Sansenya, Chankan Winyakul, Kesinee Nanok, Waya S Phutdhawong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
α-glucosidase and α-amylase inhibitory activity; diabetes type 2; type 2 diabetes mellitus
n-acetylpyrrolidine.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2020;volume=15;issue=1;spage=14;epage=25;aulast=Sansenya

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