Role of CD44 in increasing the potency of mesenchymal stem cell extracellular vesicles by hyaluronic acid in severe pneumonia

Role of CD44 in increasing the potency of mesenchymal stem cell extracellular vesicles by hyaluronic acid in severe pneumonia

Abstract Background Although promising, clinical translation of human mesenchymal stem or stromal cell-derived extracellular vesicles (MSC EV) for acute lung injury is potentially limited by significant production costs. The current study was performed to determine whether pretreatment of MSC EV wit...

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Bibliographic Details
Main Authors: Li Zhou, Qi Hao, Shinji Sugita, Yoshifumi Naito, Hongli He, Che-chung Yeh, Jae-Woo Lee
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
CD44
Extracellular vesicles
Hyaluronic acid
Mesenchymal stem cell
Pseudomonas aeruginosa pneumonia
Online Access:https://doi.org/10.1186/s13287-021-02329-2

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