Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit
Introduction. Neonatal nosocomial infection (NIs) is defined as the occurrence of infection 48 hours after birth, which is caused by a nosocomial pathogen. Newborns admitted to neonatal intensive care units (NICU) are at increased risk for developing Nis. The aim of our study was to describe risk fa...
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Medicinsko društvo za racionalnu terapiju Republike Srbije
2018-01-01
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doaj-c6e9dd0e04af4ef9a3c5f0c6db3963952020-11-25T01:41:05ZengMedicinsko društvo za racionalnu terapiju Republike SrbijeRacionalna Terapija1821-05382217-86272018-01-011029161821-05381802009DRisk factors for nosocomial infections in mechanically ventilated neonates at intensive care unitĐorđević Zorana M.0Opančina Valentina D.1Radojević-Živković Marija N.2Protrka Zoran M.3Savić Dragana M.4Rajković Gordana5Ristić Dragana6Janković Slobodan M.7Klinika za epidemiologiju, Klinički centar, KragujevacUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za radiologijuKlinički centar Kragujevac, Klinika za onkologijuUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za ginekologiju i akušerstvoUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za pedijatriju + Klinički centar Kragujevac, Klinika za pedijatrijuUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za pedijatriju + Klinički centar Kragujevac, Klinika za pedijatrijuUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za pedijatriju + Klinički centar Kragujevac, Klinika za pedijatrijuUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za farmakologiju i toksikologijuIntroduction. Neonatal nosocomial infection (NIs) is defined as the occurrence of infection 48 hours after birth, which is caused by a nosocomial pathogen. Newborns admitted to neonatal intensive care units (NICU) are at increased risk for developing Nis. The aim of our study was to describe risk factors for NIs at mechanically ventilated (MV) neonates in a NICU. Materials and methods. The study was designed as a case/control study nested in the prospective cohort study. The study population consisted of the neonates supported by MV and admitted at the NICU. Risk factors were identified and their influence quantified by logistic regression. Results. Our study showed that MV neonates in the NICU, who were longer carrying peripheral venous catheter (PVC) and spend more time in hospital, were more likely to get NIs (OR=1.091, CI=1.035-1.151). The neonates having an infection on admittance were less likely to acquire NIs. Conclusions. Development of NIs in MV neonates could be prevented by education of hospital staff and shortening of hospitalization. Rate of nosocomial infections will drop if exposure of newborns to pathogens from hospital environment and to invasive devices is decreased.https://scindeks-clanci.ceon.rs/data/pdf/1821-0538/2018/1821-05381802009D.pdfnosocomial infectionsmechanic ventilationneonatesintensive care unit |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Đorđević Zorana M. Opančina Valentina D. Radojević-Živković Marija N. Protrka Zoran M. Savić Dragana M. Rajković Gordana Ristić Dragana Janković Slobodan M. |
spellingShingle |
Đorđević Zorana M. Opančina Valentina D. Radojević-Živković Marija N. Protrka Zoran M. Savić Dragana M. Rajković Gordana Ristić Dragana Janković Slobodan M. Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit Racionalna Terapija nosocomial infections mechanic ventilation neonates intensive care unit |
author_facet |
Đorđević Zorana M. Opančina Valentina D. Radojević-Živković Marija N. Protrka Zoran M. Savić Dragana M. Rajković Gordana Ristić Dragana Janković Slobodan M. |
author_sort |
Đorđević Zorana M. |
title |
Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit |
title_short |
Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit |
title_full |
Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit |
title_fullStr |
Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit |
title_full_unstemmed |
Risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit |
title_sort |
risk factors for nosocomial infections in mechanically ventilated neonates at intensive care unit |
publisher |
Medicinsko društvo za racionalnu terapiju Republike Srbije |
series |
Racionalna Terapija |
issn |
1821-0538 2217-8627 |
publishDate |
2018-01-01 |
description |
Introduction. Neonatal nosocomial infection (NIs) is defined as the occurrence of infection 48 hours after birth, which is caused by a nosocomial pathogen. Newborns admitted to neonatal intensive care units (NICU) are at increased risk for developing Nis. The aim of our study was to describe risk factors for NIs at mechanically ventilated (MV) neonates in a NICU. Materials and methods. The study was designed as a case/control study nested in the prospective cohort study. The study population consisted of the neonates supported by MV and admitted at the NICU. Risk factors were identified and their influence quantified by logistic regression. Results. Our study showed that MV neonates in the NICU, who were longer carrying peripheral venous catheter (PVC) and spend more time in hospital, were more likely to get NIs (OR=1.091, CI=1.035-1.151). The neonates having an infection on admittance were less likely to acquire NIs. Conclusions. Development of NIs in MV neonates could be prevented by education of hospital staff and shortening of hospitalization. Rate of nosocomial infections will drop if exposure of newborns to pathogens from hospital environment and to invasive devices is decreased. |
topic |
nosocomial infections mechanic ventilation neonates intensive care unit |
url |
https://scindeks-clanci.ceon.rs/data/pdf/1821-0538/2018/1821-05381802009D.pdf |
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