Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway

Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway

Acetaminophen (APAP) is a well-known antipyretic and analgesic drug. However, the accidental or intentional APAP overdose will induce liver injury and even acute liver failure. Astragaloside IV (AS-IV), a bioactive compound isolated from Astragali Radix, has been reported to have protective effects...

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Bibliographic Details
Main Authors: Lei Li, Wenxiang Huang, Shoukai Wang, Kecheng Sun, Wenxue Zhang, Yanmei Ding, Le Zhang, Bayaer Tumen, Lili Ji, Chang Liu
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
Astragaloside IV
anti-oxidation
acetaminophen
liver injury
Online Access:http://www.mdpi.com/1420-3049/23/8/2032

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