IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER

The study investigated the distribution of polymorphous variants of genes regulating cellular cycle – p53 G215C, Bax G248A and Bcl-2 C938A in lung cancer patients and healthy donors with the purpose of obtaining new fundamental knowledge on the role of above polymorphisms in the lung cancer developm...

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Main Authors:	A. I. Dmitrieva, V. A. Serebryakova, I. A. Kuznetsova, S. S. Rakitin, L. A. Kudyakov, V. V. Novitskiy
Format:	Article
Language:	Russian
Published:	NEW TERRA Publishing House 2015-10-01
Series:	Tuberkulez i Bolezni Lëgkih
Subjects:	p53 bax bcl-2 polymorphism genes regulators of cellular circle lung cancer
Online Access:	https://www.tibl-journal.com/jour/article/view/807

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spelling	doaj-c6ffe3e21bf2407c80542041acbbd9182021-07-28T20:57:42ZrusNEW TERRA Publishing HouseTuberkulez i Bolezni Lëgkih2075-12302542-15062015-10-010105053807IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCERA. I. Dmitrieva0V. A. Serebryakova1I. A. Kuznetsova2S. S. Rakitin3L. A. Kudyakov4V. V. Novitskiy5Siberian State Medical University; Tomsk Regional Oncology DispensarySiberian State Medical University; Tomsk Regional Oncology DispensarySiberian State Medical UniversitySiberian State Medical University; Tomsk Regional Oncology DispensaryTomsk Regional Oncology DispensarySiberian State Medical University; Research Institute of Tomsk State UniversityThe study investigated the distribution of polymorphous variants of genes regulating cellular cycle – p53 G215C, Bax G248A and Bcl-2 C938A in lung cancer patients and healthy donors with the purpose of obtaining new fundamental knowledge on the role of above polymorphisms in the lung cancer development. The statistically significant di\|erences were found out in the distribution of polymorphous variants of genes regulating cellular cycle in the compared groups; relative risks of cancer development were calculated for those carrying of polymorphous variants of genes of p53 G215C, Bax G248A and Bcl-2 C938A.https://www.tibl-journal.com/jour/article/view/807p53baxbcl-2p53baxbcl-2polymorphismgenes regulators of cellular circlelung cancer
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	A. I. Dmitrieva V. A. Serebryakova I. A. Kuznetsova S. S. Rakitin L. A. Kudyakov V. V. Novitskiy
spellingShingle	A. I. Dmitrieva V. A. Serebryakova I. A. Kuznetsova S. S. Rakitin L. A. Kudyakov V. V. Novitskiy IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER Tuberkulez i Bolezni Lëgkih p53 bax bcl-2 p53 bax bcl-2 polymorphism genes regulators of cellular circle lung cancer
author_facet	A. I. Dmitrieva V. A. Serebryakova I. A. Kuznetsova S. S. Rakitin L. A. Kudyakov V. V. Novitskiy
author_sort	A. I. Dmitrieva
title	IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER
title_short	IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER
title_full	IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER
title_fullStr	IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER
title_full_unstemmed	IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER
title_sort	identification of polymorphous variants of genes regulating cellular cycle in case of lung cancer
publisher	NEW TERRA Publishing House
series	Tuberkulez i Bolezni Lëgkih
issn	2075-1230 2542-1506
publishDate	2015-10-01
description	The study investigated the distribution of polymorphous variants of genes regulating cellular cycle – p53 G215C, Bax G248A and Bcl-2 C938A in lung cancer patients and healthy donors with the purpose of obtaining new fundamental knowledge on the role of above polymorphisms in the lung cancer development. The statistically significant di\|erences were found out in the distribution of polymorphous variants of genes regulating cellular cycle in the compared groups; relative risks of cancer development were calculated for those carrying of polymorphous variants of genes of p53 G215C, Bax G248A and Bcl-2 C938A.
topic	p53 bax bcl-2 p53 bax bcl-2 polymorphism genes regulators of cellular circle lung cancer
url	https://www.tibl-journal.com/jour/article/view/807
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IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER

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