Gadolinium-containing phosphatidylserine liposomes for molecular imaging of atherosclerosis

Gadolinium-containing phosphatidylserine liposomes for molecular imaging of atherosclerosis

Exteriorized phosphatidylserine (PS) residues in apoptotic cells trigger rapid phagocytosis by macrophage scavenger receptor pathways. Mimicking apoptosis with liposomes containing PS may represent an attractive approach for molecular imaging of atherosclerosis. We investigated the utility of parama...

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Bibliographic Details
Main Authors: Andrei Maiseyeu, Georgeta Mihai, Thomas Kampfrath, Orlando P. Simonetti, Chandan K. Sen, Sashwati Roy, Sanjay Rajagopalan, Sampath Parthasarathy
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Journal of Lipid Research
Subjects:
macrophages
apoptosis mimicking
cellular uptake
colocalization with macrophages
ApoE−/− mouse model
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306817

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http://www.sciencedirect.com/science/article/pii/S0022227520306817

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