Synthesis and Anticancer Activity of 1-(1H-Indol-3-yl)-2-(4-diarylmethylpiperazine-1-yl)ethane-1,2-dione Derivatives

Several new 1-(4-diarylmethylpiperazine-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione derivatives were synthesized by acylation of 1-diarylmethylpiperazine with 2-(1H-indol-3-yl)-2-oxoacetyl chloride. Their structures were confirmed by 1H NMR, IR, mass spectra, and elemental analysis. These compounds were...

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Bibliographic Details
Main Authors: Jun-Rong Jiang, Feng Xu, Han-Gui Wu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2016/4617454