Identification of Anaerobic Bacteria in Iranian patients with Rheumatoid Arthritis

• Main Authors: Shahb Shafeian, Mojgan Bandehpour, Sina Mirzaahmadi, Azadeh Tofighi
• Format: Article
• Language: English
• Published: Shahid Beheshti University of Medical Sciences 2013-11-01
• Series: Novelty in Biomedicine
• Subjects: Septic arthritis, anaerobic bacteria, PCR, NarG
• Online Access: http://journals.sbmu.ac.ir/index.php/nbm/article/view/5075
• ISSN: 2345-3346; 2345-3907

<p>Please cite this article as: Shafeian SH, Bandehpour M, Mirzaahmadi S, Tofighi A. Identification of Anaerobic Bacteria in patients with Rheumatoid Arthritis. . Novel Biomed 2013;1(2):39-42.</p><p><strong>Background</strong>: There is a report about the 2-5% prevalence for septic arthritis by anaerobic bacteria. The relevance between synivitis and intestinal microbial flora has been a hypothesis for ten years. The PCR with sensitivity and specificity 99% for microorganism detection in acute, chronic and relapse form of septic arthritis is helpful.</p><p><strong>Methods</strong>: In this research we designed to diagnosis intestinal anaerobic bacteria which are able to occur bacteremia or septicemia. So amplification of the <em>16srRNA</em> and <em>narG</em> genes in this type of bacteria is the best way for detection of them and followed by the treatment of the patients.</p><p><strong>Results</strong>: 100 patients with septic arthritis incidences were studied here. From these numbers 61% were bacterial arthritis and 18% were infected by anaerobic bacteria. <strong></strong></p><p><strong>Conclusion:</strong> On the base of coding of nitrate reductase, the positive samples were identified Enterobacter cloacae and Methylovorus sp. O157   Escherichia coli and Borrelia garinii.</p>