CDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-κB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus

CDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-κB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus

2-Cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid methyl ester (CDDO-Me) is a triterpenoid analogue of oleanolic acid that has anti-inflammatory, antioxidant, and neuroprotective activities. In the present study, we evaluate the effects of CDDO-Me on serum extravasation and astroglial death in the...

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Bibliographic Details
Main Authors:	Min-Ju Kim, Hana Park, Seo-Hyeon Choi, Min-Jeong Kong, Ji-Eun Kim, Tae-Cheon Kang
Format:	Article
Language:	English
Published:	MDPI AG 2019-09-01
Series:	International Journal of Molecular Sciences
Subjects:	akt astrocyte bbb enos microglia pi3k seizure smi-71
Online Access:	https://www.mdpi.com/1422-0067/20/19/4862

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