Synthesis and Characterization of Some New Bis-Chalconesand Their Transformation to Bis-Thiocarbamoyl-2- Pyrazoline Derivatives
The starting materials alkoxy and benzyloxyacetophenones (1a-j, 2 and 3) have been prepared on the basis of Williamson synthesis of ether. The prepared and the available starting materials were reacted with terphthalaldehyde using green methods, Ultrasound , Microwave and solvent-free grinding metho...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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University of Zakho
2013-06-01
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| Series: | Science Journal of University of Zakho |
| Subjects: | |
| Online Access: | https://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/68 |
| Summary: | The starting materials alkoxy and benzyloxyacetophenones (1a-j, 2 and 3) have been prepared on the basis of Williamson synthesis of ether. The prepared and the available starting materials were reacted with terphthalaldehyde using green methods, Ultrasound , Microwave and solvent-free grinding method to give anew series of bis- chalcones (4a-s).The prepared bis- chalcones were subjected to react with thiosemicarbazide according to the Michael addition reaction to afford new biologically active bis-pyrazolinedeivatives(5a-s). The structure of the synthesized compounds were characterized by spectral methods: FT-IR, 1H-nmr, 13C-nmr andMass spectrometry. |
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| ISSN: | 2663-628X 2663-6298 |