Co-expression of the CBFβ-MYH11 and BCR-ABL fusion genes in chronic myeloid leukaemia / Coexistenţa genelor de fuziune CBFβ-MYH11 şi BCR-ABL în leucemia mieloidă cronică
Coexistenţa t(9;22) şi a inv(16) a fost descrisă într-un număr limitat de cazuri de LMC, LAM de novo sau LAM post chimioterapie. Raportăm un pacient cu LMC care a prezentat atât inversie de 16 cât şi cromozom Philadelphia şi care a evoluat spre criză blastică sub tratament cu Imatinib. Diagnosicul d...
Main Authors: | Popescu Roxana, Dăscălescu Angela, Dănăilă Cătălin, Ghiorghiu Doramina, Zlei Mihaela, Ivanov Anca, Sireteanu Adriana, Gorduza Eusebiu Vlad, Azoicăi Doina |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2015-06-01
|
Series: | Romanian Journal of Laboratory Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1515/rrlm-2015-0013 |
Similar Items
-
Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I
by: Mian Afsar, et al.
Published: (2012-09-01) -
“Preleukemic or smoldering” chronic myelogenous leukemia (CML):BCR-ABL1 positive: A brief case report
by: John M. Bennett, et al.
Published: (2015-01-01) -
Primary peritoneal myeloid sarcoma in association with CBFB/MYH11 fusion
by: Justin J. Kuhlman, et al.
Published: (2021-01-01) -
Successful treatment with ABL tyrosine kinase inhibitor for patients with acute myeloid leukemia with BCR-ABL1
by: Asako Takeuchi, et al.
Published: (2021-01-01) -
Acute myeloid leukemia with inv(16)(p13.1q22) and deletion of the 5’MYH11/3’CBFB gene fusion: a report of two cases and literature review
by: Lili Lv, et al.
Published: (2020-01-01)