Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes

Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes

Type 2 diabetes (T2D) is thought to be a complication of metabolic syndrome caused by disorders of energy utilization and storage and characterized by insulin resistance or deficiency of insulin secretion. Though the mechanism linking obesity to the development of T2D is complex and unintelligible,...

Full description

Bibliographic Details
Main Authors:	Jie-Ru Liu, Zhao-Hui Deng, Xiao-Juan Zhu, Yu-Rong Zeng, Xiang-Xiang Guan, Jiang-Hua Li
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2021/9924314

Similar Items

The association between nicotinamide N-methyltransferase gene polymorphisms and primary hypertension in Chinese Han Population
by: Xiang-Xiang Guan, et al.
Published: (2021-03-01)

Association between Nicotinamide N-Methyltransferase Gene Polymorphisms and Obesity in Chinese Han Male College Students
by: Qiong Zhou, et al.
Published: (2017-01-01)

Physiological Study on Association between Nicotinamide N-Methyltransferase Gene Polymorphisms and Hyperlipidemia
by: Xiao-Juan Zhu, et al.
Published: (2016-01-01)

The role of nicotinamide N-methyltransferase in Parkinson's disease
by: Thomas, Martin Geoffrey
Published: (2015)

Regulation of Nicotinamide N-methyltransferase Expression in Adipocytes
by: Ehebauer, Franziska
Published: (2020)

Nicotinamide -Methyltransferase in Health and Cancer
by: David B Ramsden, et al.
Published: (2017-06-01)

Modulation der Fettzellfunktion durch die Nicotinamid-N-Methyltransferase
by: Kraus, Nils Arne
Published: (2020)

Nicotinamide -Methyltransferase: Genomic Connection to Disease
by: David B Ramsden, et al.
Published: (2020-06-01)

Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization
by: Yanzhong Wang, et al.
Published: (2019-05-01)

Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis
by: Do In-Gu, et al.
Published: (2009-02-01)

Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation
by: Annalisa Roberti, et al.
Published: (2021-03-01)

Nicotinamide N-Methyltransferase Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer
by: Miaowei Wu, et al.
Published: (2020-10-01)

Novel Inhibitors of Nicotinamide-<i>N</i>-Methyltransferase for the Treatment of Metabolic Disorders
by: Aimo Kannt, et al.
Published: (2021-02-01)

Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy.
by: Kathrin Schmeisser, et al.
Published: (2018-09-01)

Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer
by: Renata Novak Kujundžić, et al.
Published: (2021-05-01)

Effects of Nicotinamide N-Methyltransferase on PANC-1 Cells Proliferation, Metastatic Potential and Survival Under Metabolic Stress
by: Tao Yu, et al.
Published: (2015-01-01)

Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
by: Catherine M. Sampson, et al.
Published: (2021-03-01)

High stromal nicotinamide N‐methyltransferase (NNMT) indicates poor prognosis in colorectal cancer
by: Mengmeng Song, et al.
Published: (2020-03-01)

Patients with low nicotinamide N-methyltransferase expression benefit significantly from bevacizumab treatment in ovarian cancer
by: Jun Li, et al.
Published: (2021-01-01)

The Utility of Nicotinamide N-Methyltransferase as a Potential Biomarker to Predict the Oncological Outcomes for Urological Cancers: An Update
by: Roberto Campagna, et al.
Published: (2021-08-01)

Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells
by: Haitao Yu, et al.
Published: (2020-05-01)

RNA-mediated gene silencing of nicotinamide N-methyltransferase is associated with decreased tumorigenicity in human oral carcinoma cells.
by: Valentina Pozzi, et al.
Published: (2013-01-01)

Prognostic Value of Nicotinamide N-Methyltransferase Expression in Patients With Solid Tumors: A Systematic Review and Meta-Analysis
by: Shimeng Li, et al.
Published: (2018-10-01)

Nicotinamide N-Methyltransferase Suppression Participates in Nickel-Induced Histone H3 Lysine9 Dimethylation in BEAS-2B Cells
by: Qian Li, et al.
Published: (2017-04-01)

Down-regulation of nicotinamide N-methyltransferase induces apoptosis in human breast cancer cells via the mitochondria-mediated pathway.
by: Jun Zhang, et al.
Published: (2014-01-01)

Correction: Down-Regulation of Nicotinamide N-methyltransferase Induces Apoptosis in Human Breast Cancer Cells via the Mitochondria-Mediated Pathway
by: The Staff
Published: (2014-01-01)

Correction: Down-Regulation of Nicotinamide N-methyltransferase Induces Apoptosis in Human Breast Cancer Cells via the Mitochondria-Mediated Pathway.
Published: (2014-01-01)

Esterase-Sensitive Prodrugs of a Potent Bisubstrate Inhibitor of Nicotinamide <i>N</i>-Methyltransferase (NNMT) Display Cellular Activity
by: Matthijs J. van Haren, et al.
Published: (2021-09-01)

Nicotinamide-N-methyltransferase Enhances Invasive Ability of Clear Cell Renal Cell Carcinoma by Inducing Matrix Metalloprotease-2 Expression
by: Tsung-Cheng Yang, et al.
Published: (2008)

Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells
by: Duc-Hiep Bach, et al.
Published: (2018-06-01)

N-(3-Hydroxyphenyl)nicotinamide
by: Chunhua Ge, et al.
Published: (2012-05-01)

Long non-coding RNA XIST promotes osteoporosis by inhibiting the differentiation of bone marrow mesenchymal stem cell by sponging miR-29b-3p that suppresses nicotinamide N-methyltransferase
by: Jiang Yu, et al.
Published: (2021-01-01)

Effect of Nicotinamide on Experimental Induced Diabetes
by: Q. Alenzi Faris
Published: (2009-03-01)

Impaired nicotinamide adenine dinucleotide (NAD+) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment
by: Lan Fan, et al.
Published: (2020-11-01)

Lower serum nicotinamide N-methyltransferase levels in patients with bipolar disorder during acute episodes compared to healthy controls: a cross-sectional study
by: Qing Hu, et al.
Published: (2020-01-01)

Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity
by: Yi-Ru Lee, et al.
Published: (2017)

N6-methyladenosine methyltransferases: functions, regulation, and clinical potential
by: Wei Huang, et al.
Published: (2021-07-01)

Anti-diabetic effects of S. aegyptiaca extract on streptozotocin-nicotinamide induced type 2 diabetes rats
by: Fazel Albosof, et al.
Published: (2018-03-01)

Aquabis(nicotinamide-κN)(thiocyanato-κN)copper(II)
by: Changlun Shao, et al.
Published: (2008-02-01)

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
by: Rachel S. Fletcher, et al.
Published: (2017-08-01)