Acute pretreatment with chloroquine attenuates renal I/R injury in rats.

Acute pretreatment with chloroquine attenuates renal I/R injury in rats.

BACKGROUND: Acute kidney injury (AKI) still remains an unresolved problem in pharmacotherapy and renal inflammation is a major factor in its development. Chloroquine, a well-known antimalarial drug, posses pleitropic effects as well: antiinflammatory, anticoagulant and vascular actions. The effects...

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Bibliographic Details
Main Authors: Zoran Todorovic, Branislava Medic, Gordana Basta-Jovanovic, Sanja Radojevic Skodric, Radan Stojanovic, Branislav Rovcanin, Milica Prostran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3969327?pdf=render

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