On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models

This paper presents an on-the-fly uniformization technique for the analysis of time-inhomogeneous Markov population models. This technique is applicable to models with infinite state spaces and unbounded rates, which are, for instance, encountered in the realm of biochemical reaction networks. To de...

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Main Authors: Aleksandr Andreychenko, Pepijn Crouzen, Linar Mikeev, Verena Wolf
Format: Article
Language:English
Published: Open Publishing Association 2011-07-01
Series:Electronic Proceedings in Theoretical Computer Science
Online Access:http://arxiv.org/pdf/1006.4425v1
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spelling doaj-c7965347e36547f6a3191cb14da44cbe2020-11-24T23:10:18ZengOpen Publishing AssociationElectronic Proceedings in Theoretical Computer Science2075-21802011-07-0157Proc. QAPL 201111510.4204/EPTCS.57.1On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population ModelsAleksandr AndreychenkoPepijn CrouzenLinar MikeevVerena WolfThis paper presents an on-the-fly uniformization technique for the analysis of time-inhomogeneous Markov population models. This technique is applicable to models with infinite state spaces and unbounded rates, which are, for instance, encountered in the realm of biochemical reaction networks. To deal with the infinite state space, we dynamically maintain a finite subset of the states where most of the probability mass is located. This approach yields an underapproximation of the original, infinite system. We present experimental results to show the applicability of our technique.http://arxiv.org/pdf/1006.4425v1
collection DOAJ
language English
format Article
sources DOAJ
author Aleksandr Andreychenko
Pepijn Crouzen
Linar Mikeev
Verena Wolf
spellingShingle Aleksandr Andreychenko
Pepijn Crouzen
Linar Mikeev
Verena Wolf
On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models
Electronic Proceedings in Theoretical Computer Science
author_facet Aleksandr Andreychenko
Pepijn Crouzen
Linar Mikeev
Verena Wolf
author_sort Aleksandr Andreychenko
title On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models
title_short On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models
title_full On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models
title_fullStr On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models
title_full_unstemmed On-the-fly Uniformization of Time-Inhomogeneous Infinite Markov Population Models
title_sort on-the-fly uniformization of time-inhomogeneous infinite markov population models
publisher Open Publishing Association
series Electronic Proceedings in Theoretical Computer Science
issn 2075-2180
publishDate 2011-07-01
description This paper presents an on-the-fly uniformization technique for the analysis of time-inhomogeneous Markov population models. This technique is applicable to models with infinite state spaces and unbounded rates, which are, for instance, encountered in the realm of biochemical reaction networks. To deal with the infinite state space, we dynamically maintain a finite subset of the states where most of the probability mass is located. This approach yields an underapproximation of the original, infinite system. We present experimental results to show the applicability of our technique.
url http://arxiv.org/pdf/1006.4425v1
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AT pepijncrouzen ontheflyuniformizationoftimeinhomogeneousinfinitemarkovpopulationmodels
AT linarmikeev ontheflyuniformizationoftimeinhomogeneousinfinitemarkovpopulationmodels
AT verenawolf ontheflyuniformizationoftimeinhomogeneousinfinitemarkovpopulationmodels
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