New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240
Four new prenylxanthones, emerixanthones A–D (1–4), together with six known analogues (5–10), were isolated from the culture of the deep-sea sediment derived fungus Emericella sp. SCSIO 05240, which was identified on the basis of morphology and ITS sequence analysis. The newstructures were determine...
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2014-05-01
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Series: | Marine Drugs |
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doaj-c7a8bf887bd64a5284d7505053024ae32020-11-25T01:05:36ZengMDPI AGMarine Drugs1660-33972014-05-011263190320210.3390/md12063190md12063190New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240Mangaladoss Fredimoses0Xuefeng Zhou1Xiuping Lin2Xinpeng Tian3Wen Ai4Junfeng Wang5Shengrong Liao6Juan Liu7Bin Yang8Xianwen Yang9Yonghong Liu10Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, ChinaFour new prenylxanthones, emerixanthones A–D (1–4), together with six known analogues (5–10), were isolated from the culture of the deep-sea sediment derived fungus Emericella sp. SCSIO 05240, which was identified on the basis of morphology and ITS sequence analysis. The newstructures were determined by NMR (1H, 13C NMR, HSQC, HMBC, and 1H-1H COSY), MS, CD, and optical rotation analysis. The absolute configuration of prenylxanthone skeleton was also confirmed by the X-ray crystallographic analysis. Compounds 1and 3 showed weak antibacterial activities, and 4 displayed mild antifungal activities against agricultural pathogens.http://www.mdpi.com/1660-3397/12/6/3190prenylxanthoneEmericelladeep-seafungus |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mangaladoss Fredimoses Xuefeng Zhou Xiuping Lin Xinpeng Tian Wen Ai Junfeng Wang Shengrong Liao Juan Liu Bin Yang Xianwen Yang Yonghong Liu |
spellingShingle |
Mangaladoss Fredimoses Xuefeng Zhou Xiuping Lin Xinpeng Tian Wen Ai Junfeng Wang Shengrong Liao Juan Liu Bin Yang Xianwen Yang Yonghong Liu New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240 Marine Drugs prenylxanthone Emericella deep-sea fungus |
author_facet |
Mangaladoss Fredimoses Xuefeng Zhou Xiuping Lin Xinpeng Tian Wen Ai Junfeng Wang Shengrong Liao Juan Liu Bin Yang Xianwen Yang Yonghong Liu |
author_sort |
Mangaladoss Fredimoses |
title |
New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240 |
title_short |
New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240 |
title_full |
New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240 |
title_fullStr |
New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240 |
title_full_unstemmed |
New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240 |
title_sort |
new prenylxanthones from the deep-sea derived fungus emericella sp. scsio 05240 |
publisher |
MDPI AG |
series |
Marine Drugs |
issn |
1660-3397 |
publishDate |
2014-05-01 |
description |
Four new prenylxanthones, emerixanthones A–D (1–4), together with six known analogues (5–10), were isolated from the culture of the deep-sea sediment derived fungus Emericella sp. SCSIO 05240, which was identified on the basis of morphology and ITS sequence analysis. The newstructures were determined by NMR (1H, 13C NMR, HSQC, HMBC, and 1H-1H COSY), MS, CD, and optical rotation analysis. The absolute configuration of prenylxanthone skeleton was also confirmed by the X-ray crystallographic analysis. Compounds 1and 3 showed weak antibacterial activities, and 4 displayed mild antifungal activities against agricultural pathogens. |
topic |
prenylxanthone Emericella deep-sea fungus |
url |
http://www.mdpi.com/1660-3397/12/6/3190 |
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