RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia

RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia

Abstract Background Aging is affected by genetic and environmental factors, and cigarette smoking is strongly associated with accumulation of senescent cells. In this study, we wanted to identify genes that may potentially be beneficial for cell survival in response to cigarette smoke and thereby ma...

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Bibliographic Details
Main Authors: Hannah Voic, Xiuying Li, Jun-Ho Jang, Chunbin Zou, Prithu Sundd, Jonathan Alder, Mauricio Rojas, Divay Chandra, Scott Randell, Rama K. Mallampalli, Yohannes Tesfaigzi, Tyrone Ryba, Toru Nyunoya
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Genomics
Subjects:
Replicative senescence
Primary human bronchial epithelial cells
RNA-seq
Cigarette smoke
Online Access:http://link.springer.com/article/10.1186/s12864-018-5409-z

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