Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection

Background: Although, in theory, valve-sparing aortic root replacement (David procedure) is an ideal surgical option for acute aortic dissection type A (AADA) it is usually not regarded as the first-choice treatment due to the emergency setting and the relative complexity of the procedure. Here, we...

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Main Authors: Hug Aubin, Payam Akhyari, Philipp Rellecke, Christina Pawlitza, George Petrov, Artur Lichtenberg, Hiroyuki Kamiya
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fsurg.2019.00046/full
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spelling doaj-c7d2bbadf63e4dddbfd7264f802543802020-11-24T21:52:49ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2019-08-01610.3389/fsurg.2019.00046476550Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic DissectionHug Aubin0Payam Akhyari1Philipp Rellecke2Christina Pawlitza3George Petrov4Artur Lichtenberg5Hiroyuki Kamiya6Department of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, GermanyDepartment of Cardiac Surgery, Asahikawa Medical University, Asahikawa, JapanBackground: Although, in theory, valve-sparing aortic root replacement (David procedure) is an ideal surgical option for acute aortic dissection type A (AADA) it is usually not regarded as the first-choice treatment due to the emergency setting and the relative complexity of the procedure. Here, we report the results of a consecutive, single-surgeon series of 45 AADA patients with the David procedure as first-choice treatment strategy.Methods and Results: Between September 2009 and July 2013 a total of 49 patients with AADA were consecutively operated by the same surgeon at our institution. The David procedure was the treatment of choice for the proximal aorta unless aortic valve pathology or critical preoperative patient status advocated against it. Median follow-up was 5.0 years (CI95%, 4.0–6.0). Out of the 45 patients included in this study the David procedure was performed in 28 patients (62.2%), while in 17 patients (37.8%) an alternative surgical strategy had to be pursued. Although X-clamping (168.5 ± 41.7 vs. 110.3 ± 51.1 min; p = 0.001), cardiopulmonary bypass (CPB) (245.0 ± 62.4 vs. 211.8 ± 123 min; p = 0.029) and total operation time (383.8 ± 88.5 vs. 312.8 ± 144.8; p = 0.047) were significantly longer in the David-group as compared to the non-David group, there was no difference in major complication rate as well as 30-day (17.9 vs. 23.5%; p = 0.645) and 5-year mortality (28.6 vs. 35.3%) between groups.Conclusions: This small series indicates that the David procedure may be safe and feasible as a primary surgical treatment strategy for AADA.https://www.frontiersin.org/article/10.3389/fsurg.2019.00046/fullacute aortic dissection type Avalve-sparing aortic root replacementDavid proceduretreatment strategy for aortic dissectionaortic valve repairsupracoronary replacement of the ascending aorta
collection DOAJ
language English
format Article
sources DOAJ
author Hug Aubin
Payam Akhyari
Philipp Rellecke
Christina Pawlitza
George Petrov
Artur Lichtenberg
Hiroyuki Kamiya
spellingShingle Hug Aubin
Payam Akhyari
Philipp Rellecke
Christina Pawlitza
George Petrov
Artur Lichtenberg
Hiroyuki Kamiya
Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
Frontiers in Surgery
acute aortic dissection type A
valve-sparing aortic root replacement
David procedure
treatment strategy for aortic dissection
aortic valve repair
supracoronary replacement of the ascending aorta
author_facet Hug Aubin
Payam Akhyari
Philipp Rellecke
Christina Pawlitza
George Petrov
Artur Lichtenberg
Hiroyuki Kamiya
author_sort Hug Aubin
title Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_short Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_full Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_fullStr Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_full_unstemmed Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_sort valve-sparing aortic root replacement as first-choice strategy in acute type a aortic dissection
publisher Frontiers Media S.A.
series Frontiers in Surgery
issn 2296-875X
publishDate 2019-08-01
description Background: Although, in theory, valve-sparing aortic root replacement (David procedure) is an ideal surgical option for acute aortic dissection type A (AADA) it is usually not regarded as the first-choice treatment due to the emergency setting and the relative complexity of the procedure. Here, we report the results of a consecutive, single-surgeon series of 45 AADA patients with the David procedure as first-choice treatment strategy.Methods and Results: Between September 2009 and July 2013 a total of 49 patients with AADA were consecutively operated by the same surgeon at our institution. The David procedure was the treatment of choice for the proximal aorta unless aortic valve pathology or critical preoperative patient status advocated against it. Median follow-up was 5.0 years (CI95%, 4.0–6.0). Out of the 45 patients included in this study the David procedure was performed in 28 patients (62.2%), while in 17 patients (37.8%) an alternative surgical strategy had to be pursued. Although X-clamping (168.5 ± 41.7 vs. 110.3 ± 51.1 min; p = 0.001), cardiopulmonary bypass (CPB) (245.0 ± 62.4 vs. 211.8 ± 123 min; p = 0.029) and total operation time (383.8 ± 88.5 vs. 312.8 ± 144.8; p = 0.047) were significantly longer in the David-group as compared to the non-David group, there was no difference in major complication rate as well as 30-day (17.9 vs. 23.5%; p = 0.645) and 5-year mortality (28.6 vs. 35.3%) between groups.Conclusions: This small series indicates that the David procedure may be safe and feasible as a primary surgical treatment strategy for AADA.
topic acute aortic dissection type A
valve-sparing aortic root replacement
David procedure
treatment strategy for aortic dissection
aortic valve repair
supracoronary replacement of the ascending aorta
url https://www.frontiersin.org/article/10.3389/fsurg.2019.00046/full
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