Design and synthesis of some substituted thiazolo[3,2-a]pyrimidine derivatives of potential biological activities
In continuation to our previous work, thiazolopyrimidines 2a–x were synthesized through intramolecular cyclization of 2-phenacylthio-dihydropyrimidine hydrobromides 1a–x using polyphosphoric acid. On the other hand, thiazolo[3,2-a]pyrimidine-3-one 3 was coupled with aryldiazonium salts or condensed...
Main Authors: | Samia G. Abdel Moty, Mostafa A. Hussein, Salah A. Abdel Aziz, Mahrous A. Abou-Salim |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Saudi Pharmaceutical Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016413001278 |
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