| Summary: | <p><em>Vegetable farmers are one of the populations at risk of experiencing pesticide poisoning due to their activities of spraying using pesticides. This study aims to determine the exposure of organophosphate pesticides to the decrease in the activity of the cholinesterase enzyme in the blood of vegetable farmers. This research is an analytic study with cross sectional approach. The research sample was 88 farmers in Pal Merah Village. The sampling technique was purposive sampling. The study was conducted in June to August 2019. The instruments used were questionnaire and Livibond Cholinesterase Test Kit AF267. Data collection techniques by interview and blood examination. Data were analyzed univariately and bivariately using chi square test. As many as 35 (39.8%) respondents had disguised colinestrase levels, 66 people (75.0%) had a long risk exposure, 41 people (46.6%) had poor knowledge, 20 people (22.7%) were not good in the use of PPE, 39 people (44.3%) had a BMI at risk and 36 people (40.9%) had a smoking habit. The results of bivariate analysis showed that organopathic exposure and smoking habits were related to cholinesterase levels in vegetable farmers. It is recommended that farmers always use PPE, spray in the morning and evening, spray no more than 4 hours a day</em></p><p><em><br /></em></p><p><em><em>Petani sayur merupakan salah satu populasi yang berisiko mengalami keracunan pestisida akibat aktivitasnya melakukan penyemprotan menggunakan pestisida. Penelitian ini bertujuan untuk mengetahui paparan pestisida organofosfat terhadap penurunan aktivitas enzim kolinesterase dalam darah petani sayur. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Sampel penelitian adalah petani yang ada di Kelurahan Pal Merah sebanyak 88 orang. Teknik pengambilan sampel dengan purposive sampling. Penelitian dilakukan pada bulan Juni s/d Agustus 2019. Intrumen yang digunakan adalah kuesioner dan </em><em>Livibond Cholinesterase Test Kit AF267. Teknik pengumpulan data dengan cara wawancara dan pemeriksaan darah. Data dianalisis secara univariat dan bivariat dengan menggunakan uji chi square. Sebanyak 35 (39,8%) responden memiliki kadar kolinestrase tersamar, 66 orang (75,0%) memiliki lama pajanan berisiko, 41 orang (46,6%) memiliki pengetahuan kurang baik, 20 orang (22,7%) kurang baik dalam penggunaan APD, 39 orang (44,3%) memiliki IMT berisiko dan 36 orang (40,9%) memiliki kebiasaan merokok. Hasil analisis bivariat menunjukkan bahwa paparan organopospat dan kebiasaan merokok berhubungan dengan kadar kolinesterase pada petani sayur. Untuk itu disarankan kepada petani selalu menggunakan APD, menyemprot pada pagi dan sore hari, menyemprot tidak lebih dari 4 jam sehari</em></em></p>
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