Binding of the Anti-FIV Peptide C8 to Differently Charged Membrane Models: From First Docking to Membrane Tubulation

Gp36 is the virus envelope glycoproteins catalyzing the fusion of the feline immunodeficiency virus with the host cells. The peptide C8 is a tryptophan-rich peptide corresponding to the fragment 770W-I777 of gp36 exerting antiviral activity by binding the membrane cell and inhibiting the virus entry...

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Bibliographic Details
Main Authors: Daniele Di Marino, Agostino Bruno, Manuela Grimaldi, Mario Scrima, Ilaria Stillitano, Giuseppina Amodio, Grazia Della Sala, Alice Romagnoli, Augusta De Santis, Ornella Moltedo, Paolo Remondelli, Giovanni Boccia, Gerardino D'Errico, Anna Maria D'Ursi, Vittorio Limongelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Chemistry
Subjects:
NMR
HIV
FIV
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00493/full