Mechanism of delayed conduction of fellow eyes in patients with optic neuritis
To test the hypothesis that latency delay in the fellow eyes of optic neuritis (ON) patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential (mfVEP) traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk (...
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doaj-c801a1679c1647899a3289516ee15d832020-11-24T21:08:38ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982018-02-0111232933210.18240/ijo.2018.02.24Mechanism of delayed conduction of fellow eyes in patients with optic neuritisDaniah Alshowaeir0Con Yiannikas1Clare Fraser2Alexander Klistorner3Department of Ophthalmology, University of Sydney, Sydney 2000, Australia; Department of Ophthalmology, King Saud University, Riyadh 11411, Saudi ArabiaDepartment of Neurology, Concord Hospital, Sydney 2139, Australia; Department of Neurology, Royal North Shore Hospital, Sydney 2065, AustraliaDepartment of Ophthalmology, University of Sydney, Sydney 2000, AustraliaDepartment of Ophthalmology, University of Sydney, Sydney 2000, Australia; Australian School of Advanced Medicine, Macquarie University, Sydney 2109, AustraliaTo test the hypothesis that latency delay in the fellow eyes of optic neuritis (ON) patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential (mfVEP) traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk (LR) for developing multiple sclerosis (MS) were examined separately from MS patients to isolate effect of cortical plasticity from potential pathological changes in disseminated disease. The small increase in latency in fellow eyes of LR group was statistically not significant. In MS patients, the latency was significantly delayed (P<0.02). The magnitude of the latency change in the fellow eyes did not correlate with the severity of latency delay in the affected eyes (R2<0.02, P=0.3). The differences between ON patients with and without MS, reported here, suggest that the presence of disseminated disease plays critical role in latency delay of the fellow eye.http://www.ijo.cn/en_publish/2018/2/20180224.pdf332multi-focal visual evoked potentialoptic neuritisfellow eyeslatency delay |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daniah Alshowaeir Con Yiannikas Clare Fraser Alexander Klistorner |
spellingShingle |
Daniah Alshowaeir Con Yiannikas Clare Fraser Alexander Klistorner Mechanism of delayed conduction of fellow eyes in patients with optic neuritis International Journal of Ophthalmology 332 multi-focal visual evoked potential optic neuritis fellow eyes latency delay |
author_facet |
Daniah Alshowaeir Con Yiannikas Clare Fraser Alexander Klistorner |
author_sort |
Daniah Alshowaeir |
title |
Mechanism of delayed conduction of fellow eyes in patients with optic neuritis |
title_short |
Mechanism of delayed conduction of fellow eyes in patients with optic neuritis |
title_full |
Mechanism of delayed conduction of fellow eyes in patients with optic neuritis |
title_fullStr |
Mechanism of delayed conduction of fellow eyes in patients with optic neuritis |
title_full_unstemmed |
Mechanism of delayed conduction of fellow eyes in patients with optic neuritis |
title_sort |
mechanism of delayed conduction of fellow eyes in patients with optic neuritis |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2018-02-01 |
description |
To test the hypothesis that latency delay in the fellow eyes of optic neuritis (ON) patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential (mfVEP) traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk (LR) for developing multiple sclerosis (MS) were examined separately from MS patients to isolate effect of cortical plasticity from potential pathological changes in disseminated disease. The small increase in latency in fellow eyes of LR group was statistically not significant. In MS patients, the latency was significantly delayed (P<0.02). The magnitude of the latency change in the fellow eyes did not correlate with the severity of latency delay in the affected eyes (R2<0.02, P=0.3). The differences between ON patients with and without MS, reported here, suggest that the presence of disseminated disease plays critical role in latency delay of the fellow eye. |
topic |
332 multi-focal visual evoked potential optic neuritis fellow eyes latency delay |
url |
http://www.ijo.cn/en_publish/2018/2/20180224.pdf |
work_keys_str_mv |
AT daniahalshowaeir mechanismofdelayedconductionoffelloweyesinpatientswithopticneuritis AT conyiannikas mechanismofdelayedconductionoffelloweyesinpatientswithopticneuritis AT clarefraser mechanismofdelayedconductionoffelloweyesinpatientswithopticneuritis AT alexanderklistorner mechanismofdelayedconductionoffelloweyesinpatientswithopticneuritis |
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1716760068442030080 |