A Computational Probe into the Structure and Dynamics of the Full-Length Toll-Like Receptor 3 in a Phospholipid Bilayer
Toll-like receptor 3 (TLR3) provides the host with antiviral defense by initiating an immune signaling cascade for the production of type I interferons. The X-ray structures of isolated TLR3 ectodomain (ECD) and transmembrane (TM) domains have been reported; however, the structure of a membrane-solv...
Main Authors: | Mahesh Chandra Patra, Maria Batool, Muhammad Haseeb, Sangdun Choi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/8/2857 |
Similar Items
-
Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer
by: Mahesh Chandra Patra, et al.
Published: (2018-03-01) -
Studies of cholesterol structures in phospholipid bilayers
by: Carl S. Helrich
Published: (2017-06-01) -
Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. I. Basic principles and neutron diffraction
by: Belička M., et al.
Published: (2014-12-01) -
Neutrons in studies of phospholipid bilayers
and bilayer–drug interaction. II. Small-angle scattering
by: Belička M., et al.
Published: (2014-12-01) -
Toll-Like Receptors as a Therapeutic Target in the Era of Immunotherapies
by: Mariya Farooq, et al.
Published: (2021-10-01)