Fourier transform infrared spectroscopy coupled with machine learning classification for identification of oxidative damage in freeze-dried heart valves

Abstract Freeze-drying can be used to ensure off-the-shelf availability of decellularized heart valves for cardiovascular surgery. In this study, decellularized porcine aortic heart valves were analyzed by nitroblue tetrazolium (NBT) staining and Fourier transform infrared spectroscopy (FTIR) to ide...

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Bibliographic Details
Main Authors: Dejia Liu, Sükrü Caliskan, Bita Rashidfarokhi, Harriëtte Oldenhof, Klaus Jung, Harald Sieme, Andres Hilfiker, Willem F. Wolkers
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91802-2