Bidirectional association between asthma and otitis media in children
Abstract Background This study explored the reciprocal association between otitis media and asthma in children. Methods The 2002–2013 Korean Health Insurance Review and Assessment Service-National Sample Cohort participants < 15 years old were used. In study I, 14,665 asthma patients from 2002 th...
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doaj-c8446f81753f43dea1369fc30e5598232021-01-10T12:35:59ZengBMCAllergy, Asthma & Clinical Immunology1710-14922021-01-011711810.1186/s13223-020-00500-7Bidirectional association between asthma and otitis media in childrenSo Young Kim0Hye-Rim Kim1Chanyang Min2Hyo Geun Choi3Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA UniversityDepartment of Pediatrics, CHA Bundang Medical Center, CHA UniversityHallym Data Science Laboratory, Hallym University College of MedicineHallym Data Science Laboratory, Hallym University College of MedicineAbstract Background This study explored the reciprocal association between otitis media and asthma in children. Methods The 2002–2013 Korean Health Insurance Review and Assessment Service-National Sample Cohort participants < 15 years old were used. In study I, 14,665 asthma patients from 2002 through 2005 were selected. The asthma patients were matched 1:1 with the control I group, and the occurrence of otitis media was followed until 2013. In study II, 27,043 otitis media patients from 2002 through 2005 were selected. The otitis media patients were matched 1:1 with the control II group, and the occurrence of asthma was followed until 2013. Stratified Cox proportional hazard models were used to analyze the hazard ratio (HRs) of asthma for otitis media (study I) and otitis media for asthma (study II). Results The HR for otitis media was 1.46 in asthma patients (95% confidence interval [CI] = 1.40–1.52, P < 0.001). The HR for asthma was 1.43 in otitis media patients (95% confidence interval [CI] = 1.36–1.50, P < 0.001). Conclusion Asthma and otitis media have a bidirectional association in children.https://doi.org/10.1186/s13223-020-00500-7AsthmaOtitis mediaCohort studiesEpidemiology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
So Young Kim Hye-Rim Kim Chanyang Min Hyo Geun Choi |
spellingShingle |
So Young Kim Hye-Rim Kim Chanyang Min Hyo Geun Choi Bidirectional association between asthma and otitis media in children Allergy, Asthma & Clinical Immunology Asthma Otitis media Cohort studies Epidemiology |
author_facet |
So Young Kim Hye-Rim Kim Chanyang Min Hyo Geun Choi |
author_sort |
So Young Kim |
title |
Bidirectional association between asthma and otitis media in children |
title_short |
Bidirectional association between asthma and otitis media in children |
title_full |
Bidirectional association between asthma and otitis media in children |
title_fullStr |
Bidirectional association between asthma and otitis media in children |
title_full_unstemmed |
Bidirectional association between asthma and otitis media in children |
title_sort |
bidirectional association between asthma and otitis media in children |
publisher |
BMC |
series |
Allergy, Asthma & Clinical Immunology |
issn |
1710-1492 |
publishDate |
2021-01-01 |
description |
Abstract Background This study explored the reciprocal association between otitis media and asthma in children. Methods The 2002–2013 Korean Health Insurance Review and Assessment Service-National Sample Cohort participants < 15 years old were used. In study I, 14,665 asthma patients from 2002 through 2005 were selected. The asthma patients were matched 1:1 with the control I group, and the occurrence of otitis media was followed until 2013. In study II, 27,043 otitis media patients from 2002 through 2005 were selected. The otitis media patients were matched 1:1 with the control II group, and the occurrence of asthma was followed until 2013. Stratified Cox proportional hazard models were used to analyze the hazard ratio (HRs) of asthma for otitis media (study I) and otitis media for asthma (study II). Results The HR for otitis media was 1.46 in asthma patients (95% confidence interval [CI] = 1.40–1.52, P < 0.001). The HR for asthma was 1.43 in otitis media patients (95% confidence interval [CI] = 1.36–1.50, P < 0.001). Conclusion Asthma and otitis media have a bidirectional association in children. |
topic |
Asthma Otitis media Cohort studies Epidemiology |
url |
https://doi.org/10.1186/s13223-020-00500-7 |
work_keys_str_mv |
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