Identification of host proteins differentially associated with HIV-1 RNA splice variants

Identification of host proteins differentially associated with HIV-1 RNA splice variants

HIV-1 generates unspliced (US), partially spliced (PS), and completely spliced (CS) classes of RNAs, each playing distinct roles in viral replication. Elucidating their host protein ‘interactomes’ is crucial to understanding virus-host interplay. Here, we present HyPR-MSSV for isolation of US, PS, a...

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Bibliographic Details
Main Authors: Rachel Knoener, Edward Evans III, Jordan T Becker, Mark Scalf, Bayleigh Benner, Nathan M Sherer, Lloyd M Smith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
HIV
splicing
proteomics
RNA binding proteins
RNA imaging
interactome
Online Access:https://elifesciences.org/articles/62470

Internet

https://elifesciences.org/articles/62470

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