Arsenic induced histological alterations in testis of Swiss albino mice and protection by Chlorophytum borivilianum

Objective: To investigate the sodium arsenite induced damages on the reproductive system of male mice as well as to examine whether Chlorophytum borivilianum (C. borivilianum) is able to ameliorate the damages. Methods: A different group of adult Swiss albino mice was made such as control group, sod...

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Bibliographic Details
Main Authors: Garima Sharma, Madhu Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-12-01
Series:Asian Pacific Journal of Reproduction
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2305050014600403
Description
Summary:Objective: To investigate the sodium arsenite induced damages on the reproductive system of male mice as well as to examine whether Chlorophytum borivilianum (C. borivilianum) is able to ameliorate the damages. Methods: A different group of adult Swiss albino mice was made such as control group, sodium arsenite group, post combination group, pre and post combination group. After the treatment, the testis was removed, weighed and processed for histopathological observation. Cauda epididymis was used to observe abnormal sperms. Results: A highly significant depletion was found in all the germ cell populations such as spermatogonia A and B, primary and secondary spermatocytes, spermatids in arsenic treated group with respect to control whereas recovery is found in combination groups. Conclusions: The results conclude that C. borivilianum significantly protects against arsenic-induced damages.
ISSN:2305-0500