How Epigenetic Modifications Drive the Expression and Mediate the Action of PGC-1α in the Regulation of Metabolism

How Epigenetic Modifications Drive the Expression and Mediate the Action of PGC-1α in the Regulation of Metabolism

Epigenetic changes are a hallmark of short- and long-term transcriptional regulation, and hence instrumental in the control of cellular identity and plasticity. Epigenetic mechanisms leading to changes in chromatin structure, accessibility for recruitment of transcriptional complexes, and interactio...

Full description

Bibliographic Details
Main Authors: Anne I. Krämer, Christoph Handschin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
peroxisome proliferator-activated receptor γ coactivator 1α (pgc-1α)
exercise
metabolism
epigenetics
histone modification
dna methylation
micro rna
gene regulation
thermogenesis
metabolic diseases
Online Access:https://www.mdpi.com/1422-0067/20/21/5449

Internet

https://www.mdpi.com/1422-0067/20/21/5449

Similar Items