A genetic cell context-dependent role for ZEB1 in lung cancer
ZEB1 is a driver of epithelial-to-mesenchymal transition that usually promotes lung cancer in the context of KRAS mutation. Here, the authors uncover a growth suppressive role for ZEB1 in EGFRmutant lung adenocarcinoma, thus elucidating the context dependent function of this protein.
Main Authors: | Ting Zhang, Lixia Guo, Chad J. Creighton, Qiang Lu, Don L. Gibbons, Eunhee S. Yi, Bo Deng, Julian R. Molina, Zhifu Sun, Ping Yang, Yanan Yang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12231 |
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