Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds
Heroin dependence is a major health and social problem associated with increased morbidity and mortality that adversely affects social circumstances, productivity, and healthcare and law enforcement costs. In the UK and many other Western countries, both methadone and buprenorphine are recommended b...
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Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.91934 |
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doaj-c8bceb8671cd46418b0eb2099315fc632021-04-02T11:29:19ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552012-01-010301455010.4103/0976-3147.91934Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worldsPaul J Whelan0Kimberly Remski1Department of Psychiatry, Central and North West London NHS Foundation Trust, North Westminster Community Mental Health Team for Older Adults, Latimer House, London, UKDepartment of Psychiatry, Central and North West London NHS Foundation Trust, North Westminster Community Mental Health Team for Older Adults, Latimer House, London, UKHeroin dependence is a major health and social problem associated with increased morbidity and mortality that adversely affects social circumstances, productivity, and healthcare and law enforcement costs. In the UK and many other Western countries, both methadone and buprenorphine are recommended by the relevant agencies for detoxification from heroin and for opioid maintenance therapy. However, despite obvious benefits due to its unique pharmacotherapy (eg, greatly reduced risk of overdose), buprenorphine has largely failed to overtake methadone in managing opioid addiction. The experience from the developing world (based on data from India) is similar. In this article we compare the advantages and disadvantages of the use methadone and buprenorphine for the treatment of opioid addiction from both a developed and developing world perspective; and explore some of the reasons why buprenorphine has not fulfilled the expectations predicted by many in the addictions field.http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.91934addictionbuprenorphinedetoxifi cationmaintenancemethadoneopiate |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Paul J Whelan Kimberly Remski |
spellingShingle |
Paul J Whelan Kimberly Remski Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds Journal of Neurosciences in Rural Practice addiction buprenorphine detoxifi cation maintenance methadone opiate |
author_facet |
Paul J Whelan Kimberly Remski |
author_sort |
Paul J Whelan |
title |
Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds |
title_short |
Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds |
title_full |
Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds |
title_fullStr |
Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds |
title_full_unstemmed |
Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds |
title_sort |
buprenorphine vs methadone treatment: a review of evidence in both developed and developing worlds |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Journal of Neurosciences in Rural Practice |
issn |
0976-3147 0976-3155 |
publishDate |
2012-01-01 |
description |
Heroin dependence is a major health and social problem associated with increased morbidity and mortality that adversely affects social circumstances, productivity, and healthcare and law enforcement costs. In the UK and many other Western countries, both methadone and buprenorphine are recommended by the relevant agencies for detoxification from heroin and for opioid maintenance therapy. However, despite obvious benefits due to its unique pharmacotherapy (eg, greatly reduced risk of overdose), buprenorphine has largely failed to overtake methadone in managing opioid addiction. The experience from the developing world (based on data from India) is similar. In this article we compare the advantages and disadvantages of the use methadone and buprenorphine for the treatment of opioid addiction from both a developed and developing world perspective; and explore some of the reasons why buprenorphine has not fulfilled the expectations predicted by many in the addictions field. |
topic |
addiction buprenorphine detoxifi cation maintenance methadone opiate |
url |
http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.91934 |
work_keys_str_mv |
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