| Summary: | Systemic lupus erythematosus (systemic lupus erythematosus, SLE), an autoimmune <br />disease characterized by the production of antibodies against components of the cell<br />nucleus that is associated with a broad clinical manifestations. Ninety percent of cases<br />of systemic lupus erythematosus attacking a young woman with a peak incidence at 1540<br />years<br />of<br />age<br />during<br />the<br />reproductive<br />period<br />with<br />the<br />ratio<br />of<br />women<br />and<br />men<br />5:1.<br />Its<br /><br />etiology<br /><br />is unclear, allegedly associated with a specific immune response genes in the<br />major histocompatibility complex class II, HLA-DR2 and HLA DR3. Clinical<br />manifestations which appear heterogeneous and involve almost all organ systems of the<br />condition of the joints and skin of patients with mild to severe disease that attacks the<br />central nervous system, lungs, gastrointestinal tract, and kidneys. Treatment is mainly<br />aimed at controlling the symptoms of the acute attack and suppress symptoms and<br />weight at a level that can be tolerated and prevent organ damage. <br /><br />
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