Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis
Objective: The purpose of this study was to discover the population structure and genetic diversity of Inner Mongolia White Cashmere goats (IMCGs) and demonstrate the effect of inbreeding on the live body weight (LBW), cashmere yield (CY), fiber length (FL), and fiber diameter (FD) of IMCGs.Material...
Main Authors: | , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
|
Series: | Frontiers in Veterinary Science |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.665872/full |
id |
doaj-c8dfd5cd01c8427c9e157485fada8e58 |
---|---|
record_format |
Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zhiying Wang Bohan Zhou Tao Zhang Tao Zhang Xiaochun Yan Yongsheng Yu Jinquan Li Jinquan Li Jinquan Li Bujun Mei Zhixin Wang Yanjun Zhang Ruijun Wang Qi Lv Zhihong Liu Yanhong Zhao Chen Du Rui Su |
spellingShingle |
Zhiying Wang Bohan Zhou Tao Zhang Tao Zhang Xiaochun Yan Yongsheng Yu Jinquan Li Jinquan Li Jinquan Li Bujun Mei Zhixin Wang Yanjun Zhang Ruijun Wang Qi Lv Zhihong Liu Yanhong Zhao Chen Du Rui Su Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis Frontiers in Veterinary Science inner Mongolia white cashmere goats genetic diversity regression analysis population structure inbreeding |
author_facet |
Zhiying Wang Bohan Zhou Tao Zhang Tao Zhang Xiaochun Yan Yongsheng Yu Jinquan Li Jinquan Li Jinquan Li Bujun Mei Zhixin Wang Yanjun Zhang Ruijun Wang Qi Lv Zhihong Liu Yanhong Zhao Chen Du Rui Su |
author_sort |
Zhiying Wang |
title |
Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis |
title_short |
Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis |
title_full |
Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis |
title_fullStr |
Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis |
title_full_unstemmed |
Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree Analysis |
title_sort |
assessing genetic diversity and estimating the inbreeding effect on economic traits of inner mongolia white cashmere goats through pedigree analysis |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Veterinary Science |
issn |
2297-1769 |
publishDate |
2021-06-01 |
description |
Objective: The purpose of this study was to discover the population structure and genetic diversity of Inner Mongolia White Cashmere goats (IMCGs) and demonstrate the effect of inbreeding on the live body weight (LBW), cashmere yield (CY), fiber length (FL), and fiber diameter (FD) of IMCGs.Materials and Methods: All data were collected from pedigree information and production performance records of IMCGs from 1983 to 2019. The population structure and genetic diversity were analyzed by Endog 4.8 software. Inbreeding coefficients were obtained by the pedigree package in R. Then, a linear regression model was used to analyze how inbreeding influences economic traits in IMCGs. Four levels of inbreeding coefficients (Fi) were classified in this study, including Fi = 0, 0< Fi ≤ 6.25, 6.25< Fi ≤ 12.5 and Fi≥12.5. Variance analysis was performed to determine whether inbreeding levels had a significant effect on economic traits in IMCGs.Results: The proportions of rams and dams in IMCGs for breeding were relatively small, with values of 0.8 and 20.5%, respectively. The proportion of inbred animals in the entire population was high, with values up to 68.6%; however, the average inbreeding coefficient and relatedness coefficient were 4.50 and 8.48%, respectively. To date, the population has experienced 12 generations. The average generation interval obtained in the present study was 4.11 ± 0.01 years. The ram-to-son pathway was lowest (3.97 years), and the ewe-to-daughter pathway was highest (4.24 years). It was discovered that the LBW, CY, and FL increased by 3.88 kg, 208.7 g, and 1.151 cm, respectively, with every 1% increase in the inbreeding coefficient, and the FD decreased by 0.819 μm with every 1% increase in the inbreeding coefficient. Additionally, multiple comparison analysis indicated that when the inbreeding coefficient was higher than 6.25%, the LBW showed an obvious decreasing trend. The threshold value of inbreeding depression in the CY is 12.5%. However, inbreeding depression has not been observed in the FL and FD.Conclusion: Pedigree completeness needs to be further strengthened. The degree of inbreeding in this flock should be properly controlled when designing breeding programs. |
topic |
inner Mongolia white cashmere goats genetic diversity regression analysis population structure inbreeding |
url |
https://www.frontiersin.org/articles/10.3389/fvets.2021.665872/full |
work_keys_str_mv |
AT zhiyingwang assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT bohanzhou assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT taozhang assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT taozhang assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT xiaochunyan assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT yongshengyu assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT jinquanli assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT jinquanli assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT jinquanli assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT bujunmei assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT zhixinwang assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT yanjunzhang assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT ruijunwang assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT qilv assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT zhihongliu assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT yanhongzhao assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT chendu assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis AT ruisu assessinggeneticdiversityandestimatingtheinbreedingeffectoneconomictraitsofinnermongoliawhitecashmeregoatsthroughpedigreeanalysis |
_version_ |
1721363746543108096 |
spelling |
doaj-c8dfd5cd01c8427c9e157485fada8e582021-06-22T04:53:54ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-06-01810.3389/fvets.2021.665872665872Assessing Genetic Diversity and Estimating the Inbreeding Effect on Economic Traits of Inner Mongolia White Cashmere Goats Through Pedigree AnalysisZhiying Wang0Bohan Zhou1Tao Zhang2Tao Zhang3Xiaochun Yan4Yongsheng Yu5Jinquan Li6Jinquan Li7Jinquan Li8Bujun Mei9Zhixin Wang10Yanjun Zhang11Ruijun Wang12Qi Lv13Zhihong Liu14Yanhong Zhao15Chen Du16Rui Su17College of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaInner Mongolia Bigvet Co., Ltd., Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaKey Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture, Hohhot, ChinaKey Laboratory of Animal Genetics, Breeding and Reproduction in Inner Mongolia Autonomous Region, Hohhot, ChinaEngineering Research Center for Goat Genetics and Breeding, Inner Mongolia Agriculture University, Hohhot, ChinaDepartment of Agriculture, Hetao College, Hetao University, Bayannaoer, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaInner Mongolia Bigvet Co., Ltd., Hohhot, ChinaInner Mongolia Bigvet Co., Ltd., Hohhot, ChinaReproductive Medicine Center, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, ChinaObjective: The purpose of this study was to discover the population structure and genetic diversity of Inner Mongolia White Cashmere goats (IMCGs) and demonstrate the effect of inbreeding on the live body weight (LBW), cashmere yield (CY), fiber length (FL), and fiber diameter (FD) of IMCGs.Materials and Methods: All data were collected from pedigree information and production performance records of IMCGs from 1983 to 2019. The population structure and genetic diversity were analyzed by Endog 4.8 software. Inbreeding coefficients were obtained by the pedigree package in R. Then, a linear regression model was used to analyze how inbreeding influences economic traits in IMCGs. Four levels of inbreeding coefficients (Fi) were classified in this study, including Fi = 0, 0< Fi ≤ 6.25, 6.25< Fi ≤ 12.5 and Fi≥12.5. Variance analysis was performed to determine whether inbreeding levels had a significant effect on economic traits in IMCGs.Results: The proportions of rams and dams in IMCGs for breeding were relatively small, with values of 0.8 and 20.5%, respectively. The proportion of inbred animals in the entire population was high, with values up to 68.6%; however, the average inbreeding coefficient and relatedness coefficient were 4.50 and 8.48%, respectively. To date, the population has experienced 12 generations. The average generation interval obtained in the present study was 4.11 ± 0.01 years. The ram-to-son pathway was lowest (3.97 years), and the ewe-to-daughter pathway was highest (4.24 years). It was discovered that the LBW, CY, and FL increased by 3.88 kg, 208.7 g, and 1.151 cm, respectively, with every 1% increase in the inbreeding coefficient, and the FD decreased by 0.819 μm with every 1% increase in the inbreeding coefficient. Additionally, multiple comparison analysis indicated that when the inbreeding coefficient was higher than 6.25%, the LBW showed an obvious decreasing trend. The threshold value of inbreeding depression in the CY is 12.5%. However, inbreeding depression has not been observed in the FL and FD.Conclusion: Pedigree completeness needs to be further strengthened. The degree of inbreeding in this flock should be properly controlled when designing breeding programs.https://www.frontiersin.org/articles/10.3389/fvets.2021.665872/fullinner Mongolia white cashmere goatsgenetic diversityregression analysispopulation structureinbreeding |