Assessment of Chromium Levels in Patients with Prediabetes
Background: Supplementations of chromium (Cr) have been shown to exert beneficial effects for the management of type-2 diabetes, as reflected by a decline in insulin response. Prevalence of chromium deficiency in patients with prediabetes is not well understood; the aim of this study was to evaluate...
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2014-04-01
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doaj-c8e739a72e89404982900fe2aaec57502020-11-25T01:22:56ZfasVesnu Publications مجله دانشکده پزشکی اصفهان1027-75951735-854X2014-04-013227359661531Assessment of Chromium Levels in Patients with PrediabetesZahra Torabi0Rahmatollah Rafiei1Zahra Habibi2Lootfollah Fouladi3Somayeh Najafi4Sedigheh Asgary5General Practitioner, Isfahan University of Medical Sciences, Isfahan, IranAssistant Professor, Department of Internal Medicine, School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, IranGeneral Practitioner, School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, IranClinical Anatomical Pathologists, School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, IranAcquired Immune Deficiency Research Center, Isfahan University of Medical Sciences, Isfahan, IranIsfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranBackground: Supplementations of chromium (Cr) have been shown to exert beneficial effects for the management of type-2 diabetes, as reflected by a decline in insulin response. Prevalence of chromium deficiency in patients with prediabetes is not well understood; the aim of this study was to evaluated the amount of this prevalence. Methods: In this cross-sectional descriptive study, were recruited 132 patients with prediabetes. Participants were randomly selected from those referred to the Shariati hospital, Isfahan, Iran. Fasting venous blood samples were collected from participants to measure the levels of chromium, insulin, fasting blood sugar and 2-hour post load plasma glucose. Body mass index was calculated. Determination of Cr was carried out by atomic absorption spectrometry. Findings: Of 132 patients, 24 were excluded due to failure to complete the test. Among remained patients, 34 (31.5%) had chromium deficiency, and 74 (68.5%) had normal serum levels of chromium. A significant inverse relationship was found between chromium levels and age in normal group. Conclusion: Levels of chromium deficiency is relatively common in patients with prediabetes and it is necessary to eliminate chromium deficiency in screening patients for diabetes.http://jims.mui.ac.ir/index.php/jims/article/view/3350ChromiumInsulinPrediabetes |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
Zahra Torabi Rahmatollah Rafiei Zahra Habibi Lootfollah Fouladi Somayeh Najafi Sedigheh Asgary |
spellingShingle |
Zahra Torabi Rahmatollah Rafiei Zahra Habibi Lootfollah Fouladi Somayeh Najafi Sedigheh Asgary Assessment of Chromium Levels in Patients with Prediabetes مجله دانشکده پزشکی اصفهان Chromium Insulin Prediabetes |
author_facet |
Zahra Torabi Rahmatollah Rafiei Zahra Habibi Lootfollah Fouladi Somayeh Najafi Sedigheh Asgary |
author_sort |
Zahra Torabi |
title |
Assessment of Chromium Levels in Patients with Prediabetes |
title_short |
Assessment of Chromium Levels in Patients with Prediabetes |
title_full |
Assessment of Chromium Levels in Patients with Prediabetes |
title_fullStr |
Assessment of Chromium Levels in Patients with Prediabetes |
title_full_unstemmed |
Assessment of Chromium Levels in Patients with Prediabetes |
title_sort |
assessment of chromium levels in patients with prediabetes |
publisher |
Vesnu Publications |
series |
مجله دانشکده پزشکی اصفهان |
issn |
1027-7595 1735-854X |
publishDate |
2014-04-01 |
description |
Background: Supplementations of chromium (Cr) have been shown to exert beneficial effects for the management of type-2 diabetes, as reflected by a decline in insulin response. Prevalence of chromium deficiency in patients with prediabetes is not well understood; the aim of this study was to evaluated the amount of this prevalence.
Methods: In this cross-sectional descriptive study, were recruited 132 patients with prediabetes. Participants were randomly selected from those referred to the Shariati hospital, Isfahan, Iran. Fasting venous blood samples were collected from participants to measure the levels of chromium, insulin, fasting blood sugar and 2-hour post load plasma glucose. Body mass index was calculated. Determination of Cr was carried out by atomic absorption spectrometry.
Findings: Of 132 patients, 24 were excluded due to failure to complete the test. Among remained patients, 34 (31.5%) had chromium deficiency, and 74 (68.5%) had normal serum levels of chromium. A significant inverse relationship was found between chromium levels and age in normal group.
Conclusion: Levels of chromium deficiency is relatively common in patients with prediabetes and it is necessary to eliminate chromium deficiency in screening patients for diabetes. |
topic |
Chromium Insulin Prediabetes |
url |
http://jims.mui.ac.ir/index.php/jims/article/view/3350 |
work_keys_str_mv |
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