Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds

Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds

Abstract Background Diabetic wounds remain a challenging clinical problem, which requires further treatment development. Published data showed that dermis-derived stem/progenitor cells (DSPCs) display superior wound healing in vitro. The beneficial effects of DSPCs are mediated through paracrine sec...

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Bibliographic Details
Main Authors: Yu Xin, Peng Xu, Xiangsheng Wang, Yunsheng Chen, Zheng Zhang, Yixin Zhang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Human foreskin
Dermal stem/progenitor cells
Conditioned medium
Diabetic wound healing
Extracellular matrix
Online Access:https://doi.org/10.1186/s13287-020-02116-5

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